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Background and Objectives:Kimura’s disease is a rare, allergic, inflammatory disorder of unknown cause. Patients oftenpresent nontender subcutaneous swelling in the head and neck region. Lymphadenopathy, peripheral eosinophilia, and anelevated serum IgE are also present. Kimuras disease is easily mistaken for malignant tumor, and has been confused withangiolymphoid hyperplasia with eosinophilia (ALHE). The diagnosis is confirmed by a biopsy. Treatment options range fromobservation to surgical excision, steroid therapy, and radiotherapy. We summarize characteristics of clinical feature, laboratoryresults in six cases of Kimuras disease and report the results of treatment, including surgery and steroid therapy. Subjects andMethod:Between May 1999 and August 2003, six cases were diagnosized as Kimura’s disease at the Department of OtorhinolaryngologyHead & Neck Surgery at the Inha University. Six cases included four males and two females, with the mean age of47.3 years. Preoperative evaluation included CT or MRI, CBC, and urine analysis. The study was done retrospectively. Result:Primary sites were two parotid glands, one submandibular gland, two neck lymph nodes, one scalp & cheek. Complete excisionwith steroid therapy was done in all cases. Five cases had peripheral eosinophilia. All cases reveal renal involvement,postsurgical complication or recurrence. Conclusion:Steroid therapy following surgical excision is the treatment of choice fordefinitive diagnosis and initial management. Kimuras disease must be included in the differential diagnosis of unusual head andneck mass because Kimuras disease is an unusual condition and it imitates the neoplastic or imflammatory condition in the headand neck.

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