지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 609 - 615 (7page)
이용수
초록· 키워드
오류제보하기
Allergic rhinitis is the most common atopic disease in the world. However, pathogenic mechanisms of allergic rhinitis have not been fully understood. Mouse models of allergic rhinitis are a great tool that allows in vivo studies to be conducted in the state of an intact immune and respiratory system. This model system can provide many chances to find important signaling pathways and therapeutic target molecules in allergic rhinitis. To start research in allergic rhinitis with mouse, we have to make good and reliable models. Current mouse model is not perfect with many confounding variables and has some limitations to translate findings to the clinic directly. Optimal mouse model mimicking human allergic rhinitis will promise to unravel new horizon in the field of allergic rhinitis.
목차
등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
Machida I / 2005 / Effects of various anti-asthmatic agents on mite allergen-pulsed murine bone marrow-derived dendritic cells / Clin Exp Allergy 35(7):884~888
Hogan SP / 1998 / Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice / Am J Respir Crit Care Med 157(1):210~218
Wise JT / 1999 / An adoptive transfer model of allergic lung inflammation in mice is mediated by CD4+ CD62LlowCD25+ T cells / J Immunol 162(9):5592~5600
Walls RS. / 1977 / Eosinophil response to alum adjuvants: involvement of T cells in non-antigen-dependent mechanisms / Proc Soc Exp Biol Med 156(3):431~435
Gavin AL / 2006 / Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling / Science 314(5807):1936~1938
Hogan SP / 1998 / Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice / Am J Respir Crit Care Med 157(1):210~218
Wise JT / 1999 / An adoptive transfer model of allergic lung inflammation in mice is mediated by CD4+ CD62LlowCD25+ T cells / J Immunol 162(9):5592~5600
Walls RS. / 1977 / Eosinophil response to alum adjuvants: involvement of T cells in non-antigen-dependent mechanisms / Proc Soc Exp Biol Med 156(3):431~435
Gavin AL / 2006 / Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling / Science 314(5807):1936~1938
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