Kikuchi 병의 임상적 방사선학적 고찰

정필상; 이상준; 윤준식; 박세진; 김지선; 문정환

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자료유형: 학술저널

저자정보: 정필상 이상준 윤준식 박세진 김지선 문정환

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제49권 제1호

발행연도: 2006.1

수록면: 85 - 89 (5page)

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Background and Objectives：Kikuchi’s disease (histiocytic necrotizing lymphadenitis) is a rare self-limiting disorder that typically affects the cervical lymph nodes. It has been occasionally misdiagnosed as tuberculous lymphadenitis or malignant lymphoma. In this study, we analyzed the clinical and radiologic characteristics and tried to find the differential points of Kikuchis disease. Subjects and Method：Fifty-two patients who underwent, from January 1998 to December 2004, a excisional biopsy or fine needle aspiration of a cervical lymph node and diagnosed histologically with Kikuchi’s disease were enrolled in this study. We retrospectively reviewed the medical record and imaging of each patient. The patients were followed up for a period of 14 to 200 seven days. Results：Patients were 36 women and 16 men (2.3：1) with the mean age of 23.7 years old. The affected cervical lymph nodes were most commonly located in the posterior cervical triangle (Level V, 83%). Multiple and unilateral cervical lymph nodes were affected in 23 and 16 patients, respectively. The dimensions of affected lymph nodes were in the range of 1 to 2.5 cm (mean 1.73 cm). Leukopenia was observed in 21 patients (46%) fever in 24 patients (46%). CT finding of Kikuchis disease appeared to be similar to tuberculous lymphadenitis but it had more homogenous density. One patient was recurred after 104 days since she was diagnosed as Kikuchs disease by biopsy. Conclusion：The difinite diagnosis of Kikuch’s disease was determined bypathology. But half of the patients show clinical and radiologic features suggestive of Kikuch’s disease. Short term use of steroid with high index of suspicion will reduce the unnecessary open biopsy in patient with Kikuchi’s disease. (Korean J Otolaryngol 2006;49:85-9)

#괴사성 림프절염·Kikuchi 병·결핵성 림프절염. #Histiocytic necrotizing lymphadenitis·Kikuchi's disease·Tuberculous lymphadenitis.

참고문헌 (20)

참고문헌 신청

/ 1972 / Lymphadenitis showing focal reticulum cell hyperplasiawith nuclear debri and phagocytosis 35 : 379 ~ 80

/ 1983 / Necrotizing lymphadenitis 17 : 257 ~ 62

/ 1984 / Subacute necrotizing lymphadenitis 17 : 257 ~ 62

/ 1985 / Granulocytopeniain histiocytic necrotizing lymphadenitis withoutgranulocytic infiltration:Decreased CFU-C and inhibitory effect ofserum 48 : 1053 ~ 8

/ 1991 / An unusual cause of cervicallymphadenitis:Kikuchi-Fujimoto disease 13 : 823 ~ 5

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