일측성 만성 이명 환자에서 1회 경두개 자기장 치료의 단기 효과

강호민; 박문서; 이호윤; 이선규; 변재용; 여승근

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자료유형: 학술저널

저자정보: 강호민 박문서 이호윤 이선규 변재용 여승근

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제55권 제4호

발행연도: 2012.1

수록면: 216 - 221 (6page)

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Background and Objectives The repetitive Transcranial Magnetic Stimulation (rTMS) is generally performed over the course of several weeks, as its theoretical and experimental validity has been identified in repetitive procedures. If short term application of rTMS is proven to be significantly effective, more effective treatment of tinnitus can be expected. This study was conducted to measure the effect of one session of sham rTMS & one real trial of rTMS in chronic unilateral tinnitus patients. Subjects and Method rTMS stimulation of 1 Hz and 100% magnitude was given 1200 times per day to 33 patients with chronic unilateral tinnitus on their left side, between T3 and C3/T5, following the convention of the 10-20 International EEG system. Visual Analogue Scale (VAS) and Tinnitus Handicap Inventory (THI) scores were measured four times-immediately before rTMS, immediately after sham rTMS, immediately after real rTMS and two weeks after real rTMS. Results VAS and THI scores were found to show a tendency of declining. Immediately after real rTMS application, a significant decrease in VAS and THI scores was observed compared to those measured immediately before rTMS (p＜0.05). The longer the duration was, the smaller the changes in THI and VAS scores were after a single session of rTMS treatment, a finding that is statistically significant (p＜0.05). No significant changes in THI and VAS scores (p＞0.05) attributable to the direction of tinnitus were observed. Conclusion A single session rTMS is thought to be a possible adjunctive treatment for tem-porary relief of tinnitus.

#rTMS #Single #Tinnitus

참고문헌 (24)

참고문헌 신청

Arnold W / 1996 / Focal metabolic activation in the predominant left auditory cortex in patients suffering from tinnitus: a PET study with [18F]deoxyglu cose / ORL J Otorhin

Bohning DE / 2000 / Introduction and overview of TMS physics, In Transcranial magnetic stimulation in neu-ropsychiatry / American Psychiatric Press : 13 ~ 44

Cacace AT / 1999 / Cutaneous-evoked tinnitus. I. Phenomenology, psychophysics and functional imaging / Audiol Neurootol 4 (5) : 247 ~ 257

De Ridder D / 2005 / Transcranial magnetic stimulation for tinnitus: influence of tinnitus duration on stimulation parameter choice and maximal tinnitus suppression / Otol N

De Ridder D / 2006 / Primary and secondary auditory cortex stimulation for intractable tinnitus / ORL J Otorhinolaryngol Relat Spec 68 (1) : 48 ~ 55