성문하부암의 치료결과

두형탁; 현상민; 김지희; 노종렬; 최승호; 김상윤; 남순열

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자료유형: 학술저널

저자정보: 두형탁 현상민 김지희 노종렬 최승호 김상윤 남순열

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제54권 제10호

발행연도: 2011.1

수록면: 699 - 702 (4page)

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Background and Objectives Primary subglottic cancer is uncommon, so our understanding of primary subglottic cancer is limited. The purpose of this study is to review the clinical characteristics and treatment result of primary subglottic cancer from our experience. Subjects and Method During the period from Nov. 1996 to Nov. 2010, patients with primary subglottic cancer were reviewed retrospectively. The mean follow up period was 46.1 ±40.9 months. We analyzed its clinical characteristics, stage, treatment results and survival rate. Results Of 824 patients with diagnosed laryngeal cancer, 8 (0.97%) had primary subglottic cancer and hoarseness (50.0%) is the most common initial presenting symptom. The symptom of dyspnea was found in 25.0% (2/8) of the patients and squamous cell carcinoma in 75% (6/8). At the time of diagnosis, the four clinical stages of TNM, T1, T2, T3 and T4, had 1 (12.5%), 2 (25.0%), 1 (12.5%) and 4 (50.0%) patients, respectively. There were two cases of cervical lymph node metastases, N1 and N2c. No distant metastasis was found. Two groups of patients comprising of two patients each received surgery alone or radiation alone as an initial treatment; another two groups of patients comprising of two patients each received concurrent chemoradiation or surgery plus radiation therapy alone. The overall 2-year survival rate was 80.0% and 2-year disease free survival rate was 51.7% in patients with squamous cell carcinoma. Conclusion Despite the infrequency of primary subglottic cancer, it is important to understand its clinical characteristics and treatment results during the early diagnosis to make the prognosis better.

#Laryngeal neoplasm ㆍTreatment outcomes ㆍSubglottis.

참고문헌 (13)

참고문헌 신청

Dahm DJ / 1998 / Primary subglottic cancer / Laryngoscope 108 (5) : 741 ~ 746

Edge SB / 2009 / AJCC Cancer staging manual. 7th ed / Springer : 81 ~ 92

Ferlito A / 2000 / The pathology and management of subglottic cancer / Eur Arch Otorhinolaryngol 257 (3) : 168 ~ 173

Garas J / 2006 / Squamous cell carcinoma of the subglottis / Am J Otolaryngol 27 (1) : 1 ~ 4

Ministry of Health and Welfare, Republic of Korea / 2009 / 2007 Annual report of the Korea Central Cancer Registry