갑상선 유두암의 측경부 재발에서 포괄적 경부 림프절절제술과 비교한  제한적 경부 림프절절제술의 치료 성적

안동빈; 이선재; 박선균; 손진호; 박준식

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자료유형: 학술저널

저자정보: 안동빈 이선재 박선균 손진호 박준식

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제54권 제1호

발행연도: 2011.1

수록면: 62 - 68 (7page)

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Background and Objectives Therapeutic comprehensive neck dissection has been recommended for the patients with recurrent papillary thyroid carcinoma (PTC) confined to the neck after initial total thyroidectomy. However, the benefit of comprehensive neck dissection to remove asymptomatic metastatic lymph node towards improving clinical recurrences or survival is largely unproven. We analyzed the pattern of recurrence in the lateral compartment of neck and evaluated the possible application of limited lymph node dissection against comprehensive neck dissection. Subjects and Method A retrospective review was carried out for 43 patients who underwent surgical treatment for recurrent PTC in the lateral neck from 2000 to 2005, and their clinicopathological results were stratified according to the extent of surgery into two groups, the limited surgery group and the comprehensive surgery group. Results Recurrence rate in lateral neck after initial total thyroidectomy was 14.5% (43/ 296), and the most common level of recurrence was level IV (50.9%). Although limited surgery group showed a tendency toward more frequent recurrence after treatment of the first recurrence than did the comprehensive surgery group, this tendency had no statistical significance. Moreover, no patients in either group have died of PTC during over a mean follow-up period of 80 months. In the aspect of factors associated with surgical morbidity, such as operating time, duration of admission, and complication, the limited surgery group had superior results when compared to the comprehensive group. Conclusion The benefit of comprehensive neck dissection concerning recurrence and survival was not verified in the present study hence a more preservative approach could be applied to selective patients with recurrent PTC in the lateral compartment of neck.

#Thyroid carcinoma ㆍPapillary carcinoma ㆍLymphatic metastasis ㆍNeck dissection.

참고문헌 (22)

참고문헌 신청

Bardet S / 2008 / Macroscopic lymph-node involvement and neck dissection predict lymph-node recurrence in papillary thyroid carcinoma / Eur J Endocrinol 158 (4) : 551 ~ 560

Baudin E / 1998 / Microcarcinoma of the thyroid gland:the Gustave-Roussy Institute experience / Cancer 83 (3) : 553 ~ 559

Bhattacharyya N / 2003 / Surgical treatment of cervical nodal metastases in patients with papillary thyroid carcinoma / Arch Otolaryngol Head Neck Surg 129 (10) : 1101 ~ 110

Caron NR / 2006 / Selective modified radical neck dissection for papillary thyroid cancer-is level I, II and V dissection always necessary / World J Surg 30 (5) : 833 ~ 840

Cooper DS / 2009 / Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19 (11) : 1167 ~ 1