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Background: To quantify changes of left ventricular (LV) torsion in patients’ pre and post kidney transplantation. Methods: A prospective study was conducted on 48 patients who received kidney transplantation for end stage renal diseaseand without myocardial infarction. The rotation, twist and torsion of LV were studied pre and post kidney transplantation (6months post transplantation) using velocity vector imaging by echocardiography. The data is expressed as mean ± standarddeviation and compared by paired t-test at the p < 0.05 significance level. Results: Six months post kidney transplantation, left ventricular ejection fraction (from 40.33 ± 11.42 to 61.00 ± 13.68%),ratio of mitral early and late diastolic filling velocity (from 1.04 ± 0.57 to 1.21 ± 0.52), rotation of basal LV (from 4.48 ± 2.66 to5.65 ± 2.64 degree), rotation of apical LV (from 4.27 ± 3.08 to 5.50 ± 4.25 degree), LV twist (8.75 ± 4.45 to 11.14 ± 5.25degree) and torsion (from 1.06 ± 0.54 to 1.33 ± 0.61 degree/cm) were increased significantly (p < 0.05). Interventricular septumthickness (from 11.67 ± 2.39 to 9.67 ± 0.48 mm), left ventricular mass index (from 104.00 ± 16.47 to 95.50 ± 21.44 g/m2),systolic blood pressure (from 143.50 ± 34.99 to 121.50 ± 7.09 mmHg), serum blood urea nitrogen (from 42.40 ± 7.98 to 30.43± 13.85 mg/dL) and creatinine (from 4.53 ± 1.96 to 2.73 ± 2.57 mg/dL) were decreased significantly (p < 0.05). Conclusion: Kidney transplantation in end stage renal disease without myocardial infarction results in improvement in leftventricular structure, function and myocardial mechanics as detected by echocardiography and velocity vector imaging. Velocityvector imaging provided valuable information for detection and follow-up of cardiac abnormalities in patients with end stagerenal disease.

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