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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 171 - 173 (3page)
이용수
초록· 키워드
오류제보하기
Activity of acetylcholinesterase (AChE) is well known as a biomarker of exposure to organophosphate compounds in aquatic organisms. However, the effect of diethyl phthalate (DEP), a widely used plasticizer, on the chance of AChE activity is not yet known. Olive flounder (Paralichthys olivaceus) were exposed to DEP 300 and 1,000mg DEP/kg b.w. through three times of intraperitoneal injection and effects were assessed in AChE activity of brain, muscle, heart and eyes of the exposed fish. AChE activity in various tissues of flounderwas inhibited after exposure to DEP as a concentration-dependent manner, especially in brain, muscle and heart. Among tissues examined, heart is supposed to be a major part of body which is seriously damaged by DEP exposure. It indicates that DEP induces toxic effects in various organs (brain, muscle and heart), and changes of AChE activities. Such changed activities of AChE might be a useful biomarker to assess the impacts induced by phthalate esters including DEP.
목차
등록된 정보가 없습니다.
참고문헌 (12)
참고문헌 신청
/ 1961 / A new and rapid colorimetric determination of acetylcholinesterase activity : 88 ~ 95
/ 1967 / Use of fish brain acetylcholinesterase to monitor pollution by organophosphorus pesticides : 156 ~ 162
/ 1976 / A rapid and sensitive method for the quantitation of microgram quantities of protein utili- zing the principle of protein-dye binding : 248 ~ 254
/ 1990 / Charac- terization and assay conditions for use of AChE ac- tivity from several marine species in pollution moni- toring : 75 ~ 89
/ 1991 / Drinking Water Criteria Document for Phthalic Acid Esters Prepared by the Office of Health and Environmental Assessment for the Office of Water
/ 1967 / Use of fish brain acetylcholinesterase to monitor pollution by organophosphorus pesticides : 156 ~ 162
/ 1976 / A rapid and sensitive method for the quantitation of microgram quantities of protein utili- zing the principle of protein-dye binding : 248 ~ 254
/ 1990 / Charac- terization and assay conditions for use of AChE ac- tivity from several marine species in pollution moni- toring : 75 ~ 89
/ 1991 / Drinking Water Criteria Document for Phthalic Acid Esters Prepared by the Office of Health and Environmental Assessment for the Office of Water
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