지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 79 - 88 (10page)
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초록· 키워드
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The sea tangle, Laminaria japonica has long been used in Korea as a folk remedy to promote health. Gamma-amino butyric acid-enriched (5.56% of dry weight) sea tangle was obtained by fermentation with Lactobacillus brevis BJ-20 (FLJ). A suppressive effect of FLJ on carbon tetrachloride-induced hepatotoxicity has been shown previously. Alcohol administration to Sprague-Dawley rats leads to hepatotoxicity, as demonstrated by heightened levels of hepatic marker enzymes as well as increases in both the number and volume of lipid droplets as fatty liver progresses. However, FLJ attenuated alcohol-induced hepatotoxicity and the accumulation of lipid droplets following ethanol administration. Additionally, FLJ increased the activities and transcript levels of major alcohol-metabolizing enzymes, such as alcohol dehydrogenase and aldehyde dehydrogenase, and reduced blood concentrations of alcohol and acetaldehyde. These data suggest that FLJ protects against alcohol-induced hepatotoxicity and that FLJ could be used as an ingredient in functional foods to ameliorate the effects of excessive alcohol consumption.
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참고문헌 (22)
참고문헌 신청
Arun M / 2007 / Preliminary studies on antihepatotoxic effect of Physalis peruviana Linn.(Solanaceae)against carbon tetrachloride induced acute liver injury in rats / J Ethno
Bergmeyer HU / 1974 / Methods of Enzymatic Analysis / Academic Press : 28 ~
CHO, YU RAN / 2007 / Production of γ-Aminobutyric Acid (GABA) by Lactobacillus buchneriIsolated from Kimchi and its Neuroprotective Effect on Neuronal Cells / Journal of Mic
CHOI, SOO-IM / 2006 / Improvement of γ-Aminobutyric Acid (GABA) Production Using CellEntrapment of Lactobacillus brevis GABA 057 / Journal of Microbiology and Biotechnology
Castilla R / 2004 / Dual effect of ethanol on cell death in primary culture of human and rat hepatocytes / Alcohol Alcohol 39 : 290 ~ 296
Bergmeyer HU / 1974 / Methods of Enzymatic Analysis / Academic Press : 28 ~
CHO, YU RAN / 2007 / Production of γ-Aminobutyric Acid (GABA) by Lactobacillus buchneriIsolated from Kimchi and its Neuroprotective Effect on Neuronal Cells / Journal of Mic
CHOI, SOO-IM / 2006 / Improvement of γ-Aminobutyric Acid (GABA) Production Using CellEntrapment of Lactobacillus brevis GABA 057 / Journal of Microbiology and Biotechnology
Castilla R / 2004 / Dual effect of ethanol on cell death in primary culture of human and rat hepatocytes / Alcohol Alcohol 39 : 290 ~ 296
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