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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 229 - 235 (7page)
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초록· 키워드
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In an effort to develop biopolymer-based antioxidant and antibacterial materials, a chitosan-phloroglucinol conjugate was prepared and cellular antioxidant activity and minimum inhibitory concentration against foodborne pathogens and methicillin-resistantStaphylococcus aureus (MRSA) evaluated. The chitosan-phloroglucinol conjugate showed higher antioxidant activities than the unmodified chitosan (P < 0.05). The chitosan-phloroglucinol conjugate showed 62.29% reactive oxygen species scavenging activity, 56.11% lipid peroxidation inhibition activity, and 2.21-fold increase of glutathione expression in mouse macrophage cells. Additionally, the chitosan-phloroglucinol conjugate exhibited higher antibacterial activities than the unmodified chitosan, and thechitosan-phloroglucinol conjugate showed fourfold higher antibacterial activities against MRSA and clinical isolates and twofold higher activities against foodborne pathogens compared to the unmodified chitosan.
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참고문헌 (30)
참고문헌 신청
Siems WG / 1995 / 4-Hydroxynonenal formation during ischemia and reperfusion of rat small-intestine / Life Sci 57:785~789
Takahashi M / 2001 / Estimation of lipid peroxidation of live cells using a fluorescent probe, diphenyl-1-pyrenylphosphine / Free Radic Biol Med 31:164~174
Tang H / 2010 / Antibacterial action of a novel functionalized chitosan-arginine against Gram-negative bacteria / Acta Biomater 6:2562~2571
Woo JY / 2013 / Antioxidant and tyrosinase inhibitory activities of a novel chitosan-phloroglucinol conjugate / Int J Food Sci Technol 48:1172~1178
Xiao B / 2011 / Preparation and characterization of antimicrobial chitosan-N-arginine with different degrees of substitution / Carbohydr Polym 83:144~150
Takahashi M / 2001 / Estimation of lipid peroxidation of live cells using a fluorescent probe, diphenyl-1-pyrenylphosphine / Free Radic Biol Med 31:164~174
Tang H / 2010 / Antibacterial action of a novel functionalized chitosan-arginine against Gram-negative bacteria / Acta Biomater 6:2562~2571
Woo JY / 2013 / Antioxidant and tyrosinase inhibitory activities of a novel chitosan-phloroglucinol conjugate / Int J Food Sci Technol 48:1172~1178
Xiao B / 2011 / Preparation and characterization of antimicrobial chitosan-N-arginine with different degrees of substitution / Carbohydr Polym 83:144~150
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