지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 379 - 388 (10page)
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초록· 키워드
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The mechanism by which gonadotropin-releasing hormone (GnRH) and dopamine (DA) control gonadotropin (GTH) release was studied in male and female rainbow trout using cultured pituitary cells obtained at different reproductive stages. The mechanisms of follicle-stimulating hormone (FSH) release by GnRH and DA could not be determined yet. However, basal and salmon-type GnRH (sGnRH)- or chicken-II-type GnRH (cGnRH-II)- induced luteinizing hormone (LH) release increased with gonadal maturation in both sexes. LH release activity was higher after sGnRH stimulation than cGnRH-II stimulation at maturing stages in both sexes. The GnRH antagonist ([Ac-3, 4-dehydro-Pro^1, D-p-F-Phe^2, D-Trp^(3,6)] GnRH) suppressed LH release by sGnRH stimulation in a dose-dependent manner, although the effect was weak in maturing fish. The role of DA as a GTH-release inhibitory factor differs during the reproductive cycle: the inhibition of sGnRH-stimulated LH release by DA was stronger in immature fish than in maturing, ovulating, or spermiated fish. DA did not completely inhibit sGnRH-stimulated LH release, and DA alone did not alter basal LH release. Relatively high doses (10^(-6) or 10^(-5)M) of domperidone (DOM, a DA D2 antagonist) increased LH release, which did not change with reproductive stage in either sex. The potency of DOM to enhance sGnRH-stimulated LH release was higher in maturing and ovulated fish than in immature fish. These data suggest that LH release from the pituitary gland is controlled by dual neuroendocrine mechanisms by GnRH and DA in rainbow trout, as has been reported in other teleosts. The mechanism of control of FSH release, however, remains unknown.
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참고문헌 (19)
참고문헌 신청
Amano M / 1991 / Immunocytochemical demonstration of salmon GnRH and chicken GnRH-II in the brain of masu salmon,Oncorhynchus masou / J Comp Neurol 314 : 587 ~ 597
Billard R / 1984 / Advancement and synchronisation of spawning in Salmo gairdneri and S.trutta following administration of LHR-H combined or not with pimozide / Aquaculture 4
Chang JP / 1983 / Effects of pimozide and des Gly10,[D-Ala6] luteinizing hormone-releasing hormone ethylamide on serum gonadotropin concentrations,germinal vesicle migration,
Chang JP / 1990 / Differential actions of dopamine receptor subtypes on gonadotropin and growth hormone release in vitro in goldfish / Neuroendocrinology 51 : 664 ~ 674
Chang JP / 1990 / Use of a pituitary cell dispersion method and primary culture system for the studies of gonadotropin-releasing hormone action in the goldfish, Carassius aur
Billard R / 1984 / Advancement and synchronisation of spawning in Salmo gairdneri and S.trutta following administration of LHR-H combined or not with pimozide / Aquaculture 4
Chang JP / 1983 / Effects of pimozide and des Gly10,[D-Ala6] luteinizing hormone-releasing hormone ethylamide on serum gonadotropin concentrations,germinal vesicle migration,
Chang JP / 1990 / Differential actions of dopamine receptor subtypes on gonadotropin and growth hormone release in vitro in goldfish / Neuroendocrinology 51 : 664 ~ 674
Chang JP / 1990 / Use of a pituitary cell dispersion method and primary culture system for the studies of gonadotropin-releasing hormone action in the goldfish, Carassius aur
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