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- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
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- 1 - 6 (6page)
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In an effort to discover an alternative therapeutic agent against methicillin-resistant Staphylococcus aureus (MRSA), several medicinal plants and seaweeds were evaluated for its antibacterial activity against MRSA. A methanolic extract of the Phaeophyta Ecklonia stolonifera exhibited significant antibacterial activity against MRSA. To perform more detailed investigation on antibacterial activity, the methanol extract of E. stolonifera was further fractionated with organic solvents such as hexane, dimethylchloride, ethyl acetate, and n-butanol. Among them, the hexane fraction showed the strongest antibacterial activity against MRSA strains with MIC from 500 to 600 μg/mL. The fraction also exhibited a bactericidal activity against MRSA, indicating that E. stolonifera contains a bactericidal substance against MRSA.
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참고문헌 (16)
참고문헌 신청
Barna, J.C.J / 1984 / The structure and mode of action of glycopeptide antibiotics of the vancomycin group / Annual Review of Microbiology 38 : 339 ~ 357
Finland, M / 1975 / Emergence of antibiotic resistance in hospital 1935-1975 / Reviews of Infectious Diseases 1 : 4 ~ 21
Han, E.S / 2000 / Inhibitory effects of Ecklonia stolonifera on gene mutation on mouse lymphoma tk+/- locus in L5178Y-3.7.2C cell and bone marrow micronuclei formation in ddY
Hanaki, H / 1998 / Increase in glu-tamine-non-amidated muropeptides in the peptidegly-can of vancomycin-resistant Staphylococcus aureus strain Mu50 / Journal of Antimicrobial
Hara, I / 1998 / Isolation and characteriza-tion of vanadium bromoperoxidase from a marine macroalga, Ecklonia stolonifera / Journal of Inorganic Biochemistry 72 : 23 ~ 28
Finland, M / 1975 / Emergence of antibiotic resistance in hospital 1935-1975 / Reviews of Infectious Diseases 1 : 4 ~ 21
Han, E.S / 2000 / Inhibitory effects of Ecklonia stolonifera on gene mutation on mouse lymphoma tk+/- locus in L5178Y-3.7.2C cell and bone marrow micronuclei formation in ddY
Hanaki, H / 1998 / Increase in glu-tamine-non-amidated muropeptides in the peptidegly-can of vancomycin-resistant Staphylococcus aureus strain Mu50 / Journal of Antimicrobial
Hara, I / 1998 / Isolation and characteriza-tion of vanadium bromoperoxidase from a marine macroalga, Ecklonia stolonifera / Journal of Inorganic Biochemistry 72 : 23 ~ 28
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