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Background & Object: The aim of this study was to investigate the association of degree of fatigue and gastric motility, measured by EGG, with skin sympathetic tone or cardiovascular reactivity in patients with functional dyspepsia. Methods: Subjects were 56 patients with Functional dyspepsia and eight healthy people. Degree of fatigue was assessed by questionnaires consisting of subjective complaints of fatigue. Skin sympathetic tone was measured by Ryodoraku Score and Cardiovascular Reactivity was checked by Pulse diagnostic apparatus. Gastric motility was estimated by EGG. First, all patients were divided into two groups by Ryodoraku Score 40㎂(below and above). Second, they were subdivided into two groups by Cardiovascular Reactivity(decreased and increased or not decreased). Estimates were made on the extent differences of degree of fatigue or state of gastric motility in each group. Results: 1. Fatigue scores was significantly higher in females and in the Ryodoraku-Score-below-40㎂ group. It was higher in the decreased cardiovascular reactivity group than the increased group, but to no significanct extent. Also, gastric motility was better in the Ryodoraku-Score-above-40㎂ group than in the below group. Conclusions: These results suggest that degree of fatigue and gastric motility are associated with skin sympathetic tone, but not associated with cardiovascular reactivity, and that 40㎂ is a useful cutoff point in Ryodoraku Score for assessing degree of fatigue in functional dyspepsia patients.

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