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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 684 - 702 (19page)
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초록· 키워드
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This experiment was performed to determine the effect of Jibeakjihwanghwangami(JJHG) on hypertension in monocrotaline-induced hypertensive rats.
The results obtained were as follows :
1. JJHG showed a safety in cytotoxicity and toxicity of liver.
2. JJHG showed scavenging activity on DPPH free radicals and SOD-like activity.
3. JJHG showed an inhibitory effect on ACE.
4. JJHG significantly decreased blood pressure and pulse in monocrotaline-induced hypertensive rats.
5. JJHG significantly decreased the levels of plasma aldosterone in monocrotaline-induced hypertensive rats.
6. JJHG significantly decreased the levels of potassium in monocrotaline-induced hypertensive rats.
7. JJHG significantly decreased the levels of uric acid, BUN, and creatinine in monocrotaline-induced hypertensive rats.
These results suggest that JJHG might be effective in treatment and prevention of hypertension.
목차
등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
/ 2003 / JNC. Seventh Report of the Joint National Committeeon Prevention, Detection, Evaluationand Treatment of High Blood Pressure, December, 2003
Barnes JM / 1964 / Lesions in the lungs and livers of rats poisoned with the pyrrolizidine alkaloid fulvine and its N-oxide / J Pathol Bacteriol 88 : 521 ~ 531
Cushman DW / 1982 / Development and design of specific inhibitors of angiotensin-converting enzyme / Am J Cardiol 21;49 (6) : 1390 ~ 1394
Heuschmann PU / 2004 / Predictors of in-hospital mortality and attributable risks of death after ischemic stroke; the German Stroke Registers Study Group / Arch Intern Med 1
Hislop A / 1974 / Arterial changes in Crotalaria spectabilis-induced pulmonary hypertension in rats / Br J Exp Pathol 55 (2) : 155 ~ 163
Barnes JM / 1964 / Lesions in the lungs and livers of rats poisoned with the pyrrolizidine alkaloid fulvine and its N-oxide / J Pathol Bacteriol 88 : 521 ~ 531
Cushman DW / 1982 / Development and design of specific inhibitors of angiotensin-converting enzyme / Am J Cardiol 21;49 (6) : 1390 ~ 1394
Heuschmann PU / 2004 / Predictors of in-hospital mortality and attributable risks of death after ischemic stroke; the German Stroke Registers Study Group / Arch Intern Med 1
Hislop A / 1974 / Arterial changes in Crotalaria spectabilis-induced pulmonary hypertension in rats / Br J Exp Pathol 55 (2) : 155 ~ 163
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