Hippocampal Subfields Volume Reduction in High Schoolers with Previous Verbal Abuse Experiences

이상원; 유재현; 김고운; 김동찬; 박현욱; 최지욱; Martin H. Teicher; Bum Seok Jeong

Hippocampal Subfields Volume Reduction in High Schoolers with Previous Verbal Abuse Experiences

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Type: Academic journal

Author: 이상원 유재현 김고운 김동찬 박현욱 최지욱 Martin H. Teicher Bum Seok Jeong

Journal: 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제16권 제1호 KCI Accredited Journals

Published: 2018.1

Pages: 46 - 56 (11page)

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Hippocampal Subfields Volume Reduction in High Schoolers with Previous Verbal Abuse Experiences

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Objective: Reduced hippocampal volume and alterations in white matter tracts have been frequently reported in adults having the history of emotional maltreatment. We investigated whether these structural change occur in adolescents with previous verbal abuse (VA) experiences. Methods: Hippocampal subfield volume and white matter structural connectivity measures were assessed in 31 first year male high school students with various degrees of exposure to parental and peer VA. Results: The high VA group showed significant volume reduction in the left cornu ammonis (CA) 1 and left subiculum compared to the low VA group (p＜0.05). Volumes of left hippocampal subfields CA1 and subiculum were negatively correlated with previous VA experiences (p＜0.05). Increased mean diffusivity (MD) of the splenium of the corpus callosum was related to high VA score across all subjects (p＜0.05). There was an inverse relationship between volume of the CA1 and subiculum and MD of the splenium (p＜0.05). Conclusion: Exposure to parental and peer VA may affect development of the left hippocampal subfields and the splenium of corpus callosum. These structural alterations can be discernible during adolescence.

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References (93)

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