지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 249 - 255 (7page)
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초록· 키워드
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Objective To assess the prevalence of peripheral neuropathy in patients with rheumatoid arthritis (RA) having neuropathic symptoms, and to investigate the relationship between electrophysiological findings of peripheral neuropathy and clinical findings of RA.Methods Patients with a clinical diagnosis of RA and who had tingling or burning sensation in any extremity were electrophysiologically examined for evidence of peripheral neuropathy. Study parameters, including age, gender, laboratory parameters, duration of RA, and medication, were recorded. The symptoms and signs of neuropathy were quantified with the neuropathy symptom score, and the functional statuses of these patients were assessed.Results Out of a total of 30 RA patients, 10 (33%) had peripheral neuropathy: 2 had bilateral carpal tunnel syndrome (CTS), 5 had unilateral CTS, 1 had sensory polyneuropathy, and 2 had motor-sensory polyneuropathy. The mean ages of the patients with and without peripheral neuropathy were 69.4 and 56.5 years, respectively (p<0.05). A significant relationship was found between peripheral neuropathy and anti-cyclic citrullinated peptide (anti-CCP) antibody. However, no relationship was found between peripheral neuropathy and the type of medication, RA duration, the patients’ functional status, neuropathic symptoms, erythrocyte sedimentation rate, and C-reactive protein values.Conclusion Neuropathic symptoms are common in RA patients, and it is difficult to distinguish peripheral neuropathy symptoms from those of arthritis. Patients with RA, particularly elderly patients and anti-CCP antibody positive patients who complain of neuropathic symptoms should undergo electrophysiological examination.
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참고문헌 (23)
참고문헌 신청
Agarwal V / 2008 / A clinical, electrophysiological, and pathological study of neuropathy in rheumatoid arthritis / Clin Rheumatol 27 : 841 ~ 844
Aletaha D / 2010 / 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative / Arthr
Arnett FC / 1988 / The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis / Arthritis Rheum 31 : 315 ~ 324
Bayrak AO / 2010 / Electrophysiological assessment of polyneuropathic involvement in rheumatoid arthritis:relationships among demographic, clinical and laboratory findings /
Beghi E / 1998 / Chronic symmetric symptomatic polyneuropathy in the elderly: a field screening investigation of risk factors for polyneuropathy in two Italian communities.
Aletaha D / 2010 / 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative / Arthr
Arnett FC / 1988 / The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis / Arthritis Rheum 31 : 315 ~ 324
Bayrak AO / 2010 / Electrophysiological assessment of polyneuropathic involvement in rheumatoid arthritis:relationships among demographic, clinical and laboratory findings /
Beghi E / 1998 / Chronic symmetric symptomatic polyneuropathy in the elderly: a field screening investigation of risk factors for polyneuropathy in two Italian communities.
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