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자료유형
학술저널
저자정보
저널정보
대한재활의학회 Annals of Rehabilitation Medicine Annals of Rehabilitation Medicine 제29권 제4호
발행연도
2005.1
수록면
406 - 412 (7page)

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Objective: To evaluate the effects of proliferant by injecting blood into the articular cartilage defect. Method: The patella of rabbits were dislocated laterally and 2 mm circular and 2 mm depth full-thickness defect was made in the articular cartilage. We injected 0.2 cc autologous blood to the right defect and normal saline to the left one at 1 week after operation for six times with a 1 week interval. After injection for six weeks, the articular cartilage defect were obtained and stained with H-E and S-100. Results: The surface of the saline-injected group was easily distinguishable from the surrounding articular cartilage. But the blood-injected group had similar appearance to the surrounding cartilage, with the margin of the defect barely discerptible. Strong S-100 stained immune cartilage cells were observed in the blood-injected group. Conclusion: The repairing process of the injured articular cartilage using autologous blood was shown to be much better than that of saline-injected group although the observation period was short and the number of animal was small. So we found that autologous blood effectively repaired osteochondral defects.

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