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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 73 - 78 (6page)
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Background: Hepatitis B remains the most common transfusion-transmitted viral infection. We explored the current status of pre-transfusion screening and post-transfusion followup testing for hepatitis B virus (HBV) surface antigen (HBsAg) and antibodies (anti-HBs) in blood recipients from an area of high HBV endemicity.
Methods: A total of 7,780 blood recipients were transfused with at least 1 unit of blood component at a single university hospital in Korea between January 2006 and December 2009. Their medical records were reviewed, and their demographic and transfusion-related data were analyzed.
Results: Pre-transfusion HBsAg and anti-HBs levels were tested in 77.6% (6,037/7,780) of the recipients. The results varied widely according to recipient age. In all, 32.8% (1,982/ 6,037) of the recipients who were tested had dual negative pre-transfusion results for HBsAg and anti-HBs and, therefore, were at increased risk of HBV transmission. Post-transfusion follow-up testing for HBsAg and/or anti-HBs was performed in 22% (436/1,982) of the increased-risk group.
Conclusions: Our data show that current transfusion-related laboratory testing practice is not sufficient to properly investigate possible post-transfusion infections. Routine laboratory tests, including HBsAg and anti-HBs, should be recommended in transfusion guidelines.
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참고문헌 (17)
참고문헌 신청
Candotti D / 2009 / Transfusion-transmitted hepatitis B virus infection / J Hepatol 51 : 798 ~ 809
Inaba S / 2006 / Individual nucleic amplification technology does not prevent all hepatitis B virus transmission by blood donation / Transfusion 46 : 2028 ~ 2029
Iudicone P / 2009 / Hepatitis B virus blood screening: impact of nucleic amplification technology testing implementation on identifying hepatitis B surface antigen non-react
Kuhns MC / 2004 / Lack of correlation between HBsAg and HBV DNA levels in blood donors who test positive for HBsAg and anti-HBc: implications for future HBV screening policy
Liang R. / 2009 / How I treat and monitor viral hepatitis B infection in patients receiving intensive immunosuppressive therapies of undergoing hematopoietic stem cell trans
Inaba S / 2006 / Individual nucleic amplification technology does not prevent all hepatitis B virus transmission by blood donation / Transfusion 46 : 2028 ~ 2029
Iudicone P / 2009 / Hepatitis B virus blood screening: impact of nucleic amplification technology testing implementation on identifying hepatitis B surface antigen non-react
Kuhns MC / 2004 / Lack of correlation between HBsAg and HBV DNA levels in blood donors who test positive for HBsAg and anti-HBc: implications for future HBV screening policy
Liang R. / 2009 / How I treat and monitor viral hepatitis B infection in patients receiving intensive immunosuppressive therapies of undergoing hematopoietic stem cell trans
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