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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 86 - 90 (5page)
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초록· 키워드
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We present a rare case of microgranular variant acute promyelocytic leukemia (APL) associated with ider(17)(q10)t(15;17)(q22;q12) of an old-age patient. The initial chromosome study showed a 46,XX,del(6)(?q21q25),der(15)t(15;17)(q22;q12),ider(17)(q10)t(15;17) [10]/47,sl,+ider(17)(q10)t(15;17)[3]/46,XX[16]. FISH signals from a dual color dual fusion translocation PML-RARA probe were consistent with the results of conventional cytogenetics. Because of the rarity of ider(17)(q10)t(15;17) in microgranular APL, further studies on both gene dosage effect of this chromosomal abnormality and the influence of ider(17)(q10)t(15;17) on clinical features such as prognosis, survival, and treatment response of APL cases are recommended.
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참고문헌 (18)
참고문헌 신청
Cervera J / 2010 / Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy / Haematologica 95
Chou WC / 1997 / Clinical and biological characteristics of acute promyelocytic leukemia in Taiwan: a high relapse rate in patients with high initial and peak white blood cel
Hernandez JM / 2001 / Additional cytogenetic changes do not influence the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with an ATRA plus anth
Hiorns LR / 1997 / Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia / Br J Haematol 96 : 314 ~ 321
Kaleem Z / 1999 / Acute promyelocytic leukemia with additional chromosomal abnormalities and absence of Auer rods / Am J Clin Pathol 112 : 113 ~ 118
Chou WC / 1997 / Clinical and biological characteristics of acute promyelocytic leukemia in Taiwan: a high relapse rate in patients with high initial and peak white blood cel
Hernandez JM / 2001 / Additional cytogenetic changes do not influence the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with an ATRA plus anth
Hiorns LR / 1997 / Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia / Br J Haematol 96 : 314 ~ 321
Kaleem Z / 1999 / Acute promyelocytic leukemia with additional chromosomal abnormalities and absence of Auer rods / Am J Clin Pathol 112 : 113 ~ 118
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