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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 279 - 282 (4page)
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초록· 키워드
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Acinetobacter baumannii is an important microorganism responsible for a number of nosocomial outbreaks, in particular, in intensive care units (ICUs). We investigated a nosocomial infection caused by multidrug-resistant (MDR) A. baumannii in a neonatal intensive care unit (NICU) in Korea. A. baumannii isolates were characterized using Etest (AB Biodisk, Sweden), two multiplex PCR assays, and multilocus sequence typing (MLST)scheme. PCR and PCR mapping experiments were performed for detecting and characterizing the determinants of antimicrobial resistance. Eight strains isolated from an NICU belonged to European (EU) clone II and revealed only one sequence type (ST), namely,ST357. All the isolates were susceptible to imipenem but were resistant to amikacin, gentamicin,ceftazidime, cefepime, and ciprofloxacin. To the best of our knowledge, this is the first report of a nosocomial infection in an NICU in Korea caused by ST357 MDR/carbapenem-susceptible A. baumannii strains. This result demonstrates that nosocomial outbreaks of MDR/carbapenem-susceptible strains as well as MDR/carbapenem-resistant isolates may occur in NICUs.
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참고문헌 (16)
참고문헌 신청
Akasaka T / 2001 / Type II topoisomerase mutations in fluoroquinolone-resistant clinical strains of Pseudomonas aeruginosa isolated in 1998 and 1999: role of target enzyme i
Bartual SG / 2005 / Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii / J Clin Microbiol 43 : 4382 ~ 439
Bou G / 2000 / PCR-based DNA fingerprinting (REP-PCR, AP-PCR) and pulsed-field gel electrophoresis characterization of a nosocomial outbreak caused by imipenem- and meropene
Cho YJ / 2009 / Genetic basis of resistance to aminoglycosides in Acinetobacter spp. and spread of armA in Acinetobacter baumannii sequence group 1 in Korean hospitals / DIA
Clinical and Laboratory Standards Institute / 2010 / Performance standards for antimicrobial susceptibility testing. Fifteenth Informational supplement, M100?S20 / Clinical and Laborator
Bartual SG / 2005 / Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii / J Clin Microbiol 43 : 4382 ~ 439
Bou G / 2000 / PCR-based DNA fingerprinting (REP-PCR, AP-PCR) and pulsed-field gel electrophoresis characterization of a nosocomial outbreak caused by imipenem- and meropene
Cho YJ / 2009 / Genetic basis of resistance to aminoglycosides in Acinetobacter spp. and spread of armA in Acinetobacter baumannii sequence group 1 in Korean hospitals / DIA
Clinical and Laboratory Standards Institute / 2010 / Performance standards for antimicrobial susceptibility testing. Fifteenth Informational supplement, M100?S20 / Clinical and Laborator
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