지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 259 - 263 (5page)
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초록· 키워드
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Platelet satellitism is a rare phenomenon in which platelets adhere to the surface of neutrophils; in addition, platelet phagocytosis by neutrophils and monocytes is rare event. Although its clinical significance and pathophysiology are still unclear, platelet-neutrophil agglutination seems to be the end point of a process that is initiated by platelet satellitism and causes pseudothrombocytopenia and pseudoneutropenia. Differentiating pseudothrombocytopenia is essential to avoid unnecessary diagnostic testing and treatments. This report describes an unusual case of a 64 yr old man who presented with left flank pain and pseudothrombocytopenia, which was caused by platelet satellitism with platelet phagocytosis by neutrophils and platelet-neutrophil agglutination. Platelet satellitism occurred in the presence of ethylenediaminetetraacetic acid (EDTA) at room temperature or 4°C, but not at 37°C; however, platelet-neutrophil agglutination and pseudoleukopenia were observed in EDTA-treated blood only after a 2-hr incubation period at room temperature. Additionally, platelet satellitism could be induced in packed blood cells from a normal individual during a mixing assay with this patient’s plasma. To the best of my knowledge, this is the first reported case of platelet satellitism with platelet phagocytosis by neutrophils and platelet-neutrophil agglutination in Korea.
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참고문헌 (26)
참고문헌 신청
Berkman N / 1991 / EDTA-dependent pseudothrombocytopenia: a clinical study of 18 patients and a review of the literature / Am J Hematol 36 : 195 ~ 201
Bizzaro N / 1991 / qPlatelet satellitosis to polymorphonuclears: cytochemical, immunological, and ultrastructural characterization of eight cases / Am J Hematol 36 : 235 ~ 2
Bizzaro N / 1995 / EDTA-dependent pseudothrombocytopenia. Association with antiplatelet and antiphospholipid antibodies / Am J Clin Pathol 103 : 103 ~ 107
Bizzaro N / 1995 / Platelet satellitism is Fc gamma RIII (CD16) receptor-mediated / Am J Clin Pathol 103 : 740 ~ 744
Christopoulos C / 1991 / Platelet satellitism and alpha granule proteins / J Clin Pathol 44 : 788 ~ 789
Bizzaro N / 1991 / qPlatelet satellitosis to polymorphonuclears: cytochemical, immunological, and ultrastructural characterization of eight cases / Am J Hematol 36 : 235 ~ 2
Bizzaro N / 1995 / EDTA-dependent pseudothrombocytopenia. Association with antiplatelet and antiphospholipid antibodies / Am J Clin Pathol 103 : 103 ~ 107
Bizzaro N / 1995 / Platelet satellitism is Fc gamma RIII (CD16) receptor-mediated / Am J Clin Pathol 103 : 740 ~ 744
Christopoulos C / 1991 / Platelet satellitism and alpha granule proteins / J Clin Pathol 44 : 788 ~ 789
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