지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 185 - 190 (6page)
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초록· 키워드
오류제보하기
Background: In order to determine the clinical usefulness of the MicroScan (Siemens Healthcare Diagnostics, USA) MICroSTREP plus antimicrobial panel (MICroSTREP) for testing antimicrobial susceptibility of ß-hemolytic streptococci (BHS) and viridans group streptococci (VGS), we compared the accuracy of MICroSTREP with that of the CLSI reference method.
Methods: Seventy-five BHS and 59 VGS isolates were tested for antimicrobial susceptibility to ampicillin, penicillin, cefotaxime, meropenem, erythromycin, clindamycin, levofloxacin, and vancomycin by using MICroSTREP and the CLSI agar dilution method.
Results: The overall essential agreement with regard to minimum inhibitory concentrations (MICs) (within ±1 double dilution) between MICroSTREP and the CLSI reference method was 98.2%, and categorical agreement (CA) was 96.9%. For the BHS isolates, the CA for erythromycin was 96.0%, whereas that for cefotaxime, meropenem, levofloxacin, and vancomycin (for ampicillin, penicillin, and clindamycin; 98.7%) was 100%. For the VGS isolates, the CA for penicillin was 84.7% and that for erythromycin, clindamycin, and vancomycin (for meropenem, 86.5%; for ampicillin, 88.1%; and for cefotaxime and levofloxacin, 96.6%) was 100%. All categorical errors of penicillin and ampicillin in the VGS isolates were minor.
Conclusions: The accuracy of MICroSTREP is comparable to that of the CLSI reference method, suggesting that this panel can be effective for testing antimicrobial susceptibility of BHS and VGS.
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참고문헌 (15)
참고문헌 신청
Barenfanger J / 2001 / Improved antimicrobial interventions have benefits / J Clin Microbiol 39 : 2823 ~ 2828
Bisno AL / 2002 / Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis / Clin Infect Dis 35 : 113 ~ 125
Clinical and Laboratory Standards Institute / 2010 / Performance standar-ds for antimicrobial susceptibility testing; Twentieth informational supplement, M100-S20 / Clinical and Laborato
Doern GV / 1996 / Emergence of high rates of antimicrobial resistance among viridans group streptococci in the United States / Antimicrob Agents Chemother 40 : 891 ~ 894
Food and Drug Administration / 2007 / Class II special controls guidance document: antimicrobial susceptibility test (AST) systems; guidance for industry and FDA / Food and Drug Adminis
Bisno AL / 2002 / Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis / Clin Infect Dis 35 : 113 ~ 125
Clinical and Laboratory Standards Institute / 2010 / Performance standar-ds for antimicrobial susceptibility testing; Twentieth informational supplement, M100-S20 / Clinical and Laborato
Doern GV / 1996 / Emergence of high rates of antimicrobial resistance among viridans group streptococci in the United States / Antimicrob Agents Chemother 40 : 891 ~ 894
Food and Drug Administration / 2007 / Class II special controls guidance document: antimicrobial susceptibility test (AST) systems; guidance for industry and FDA / Food and Drug Adminis
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