지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 60 - 63 (4page)
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초록· 키워드
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The t(9;22)(q34;q11.2) translocation results in a BCR-ABL1 fusion gene located on the Philadelphia chromosome (Ph), causing a constitutively active BCR-ABL1 tyrosine kinase. This fusion gene is found in virtually all cases of CML, 5% of pediatric and 15-30% of adult cases of ALL, and 1-2% of cases of de novo AML [1-3]. While mixed phenotype acute leukemia (MPAL) with t(9;22)(q34;q11.2) is rare, this translocation is the most common recurrent genetic abnormality seen in MPAL [4].
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참고문헌 (13)
참고문헌 신청
Anastasi J / 1996 / Lineage involvement by BCR/ABL in Ph+ lymphoblastic leukemias: chronic myelogenous leukemia presenting in lymphoid blast vs. Ph+ acute lymphoblastic leuk
Borowitz MJ / 2008 / WHO classification of tumours of haematopoietic and lymphoid tissues / IARC : 150 ~ 155
Dohner H / 2010 / Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet / Bl
Hehlmann R / 2012 / How I treat CML blast crisis / Blood 120 : 737 ~ 747
Keung YK / 2004 / Philadelphia chromosome positive myelodysplastic syndrome and acute myeloid leukemia-retrospective study and review of literature / Leuk Res 28 : 579 ~ 586
Borowitz MJ / 2008 / WHO classification of tumours of haematopoietic and lymphoid tissues / IARC : 150 ~ 155
Dohner H / 2010 / Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet / Bl
Hehlmann R / 2012 / How I treat CML blast crisis / Blood 120 : 737 ~ 747
Keung YK / 2004 / Philadelphia chromosome positive myelodysplastic syndrome and acute myeloid leukemia-retrospective study and review of literature / Leuk Res 28 : 579 ~ 586
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