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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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For the combination of MRI and magnetic particle hyperthermia(MPH), we investigated the relative heatingefficiency with respect to the strength of the static magnetic field under which the magnetic nanoparticles areto be heated by RF magnetic field. We performed nanoparticle heating experiments at the fringe field of 3T MRImagnet with applying the RF magnetic field perpendicularly to the static magnetic field. The static field strengthswere 0T, 0.1T, 0.2T, and 0.3T. To prevent the coil heat from conducting to the nanoparticle suspension, we cooledthe heating solenoid coil with temperature-controlled water with applying heat insulators between the solenoid coiland the nanoparticle container. We observed significant decrease of heat generation, up to 6% at 0.3T(100% at 0T),due to the magnetic saturation of the nanoparticles of 15 nm diameter under the static field. We think MPH is stillfeasible at low magnetic field lower than 0.3T if stronger RF magnetic field generation is permitted.
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참고문헌 (16)
참고문헌 신청
Deatsch. / 2014 / Heating efficiency in magnetic nanoparticle Hyperthermia / J. Magn. Magn. Mater 354 : 163 ~ 172
E. Katz. / 2004 / Integrated nanoparticle-biomolecule hybrid systems:synthesis, properties, and applications / Angew. Chem. Int. Ed. 43 : 6042 ~ 6108
H. S. Cho. / 1995 / Analysis of the complications of 6 brain-dead patients / Korean J. Anes 29 : 718 ~ 723
J. L. Corchero. / 2009 / Biomedical applications of distally controlled magnetic nanoparticles / Trends Biotechnol 27 : 468 ~ 476
L. Jian. / 2013 / A novel targeted magnetic fluid hyperthermia system using HTS coil array for tumor treatment / IEEE Trans. Appl. Supercon. 23
E. Katz. / 2004 / Integrated nanoparticle-biomolecule hybrid systems:synthesis, properties, and applications / Angew. Chem. Int. Ed. 43 : 6042 ~ 6108
H. S. Cho. / 1995 / Analysis of the complications of 6 brain-dead patients / Korean J. Anes 29 : 718 ~ 723
J. L. Corchero. / 2009 / Biomedical applications of distally controlled magnetic nanoparticles / Trends Biotechnol 27 : 468 ~ 476
L. Jian. / 2013 / A novel targeted magnetic fluid hyperthermia system using HTS coil array for tumor treatment / IEEE Trans. Appl. Supercon. 23
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