지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Purpose: The purposes of this study were to measure the dose distribution of Photodynamic therapy(PDT) laser with 635 nm wavelength using GafChromic film. Method & Result: We made each output 300 J by changing mW and sec using the laser beam radiation mode such as C.W(Continuous Wave) mode, Pulse mode and Burst Pulse mode and measured the does at 0 mm and 5 mm of distance from optic fiber catheter end to the film,and at 5 mm distance by changing the angle of the end of the optic fiber catheter as 0o and 0.5o. The radiated film was scanned and OD(Optical Density) was compared. And two-dimensional isodose curves were obtained and the consistency of shapes was compared. It was confirmed that there was consistency between optic density and the dose radiated on the film when we radiated GafChromic film by changing distance and angle of 300 J output in each radiation mode coordinating mW and sec. Conclusion: In this study, we could identify the stability according to changes in laser beam modes, changes in output according to distance, changes in uniformity according to angle, and beam profiles using GafChromic film, and we could also get two-dimensional isodose curve. It was found that small change in the distance and angle that is made when optic fiber catheter was contacted on the treatment area did not make big effects on the output of beam and the uniformity of dose, and it was also found that GafChromic film could be utilized for the purpose of QA of PDT laser beam.
목차
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참고문헌 (12)
참고문헌 신청
Bjarngard BE / 1990 / Doses on the Central Axes of Narrow 6 MV X-ray Beams / Med Phys 17 : 794 ~ 799
Hampton JA / 1992 / Mechanism of Cell Killing in Photodynamic Therapy using a Novel in vivo /in vitro Light Culture System / Photochem Photobiol 56 : 235 ~ 243
Henderson BW / 1992 / How Does Photodynamic Therapy Work? / Photochem Photobiol 55 : 145 ~ 157
Hyun Soo Lim / 2003 / Biomedical Optics and Laser Treatment Optical Science and Technology 7 : 6 ~ 13
Hyun Soo Lim / 2010 / Photodynamic Cancer Therapy and Application of Laser / Gungmedia(Chungnam National University Press)
Hampton JA / 1992 / Mechanism of Cell Killing in Photodynamic Therapy using a Novel in vivo /in vitro Light Culture System / Photochem Photobiol 56 : 235 ~ 243
Henderson BW / 1992 / How Does Photodynamic Therapy Work? / Photochem Photobiol 55 : 145 ~ 157
Hyun Soo Lim / 2003 / Biomedical Optics and Laser Treatment Optical Science and Technology 7 : 6 ~ 13
Hyun Soo Lim / 2010 / Photodynamic Cancer Therapy and Application of Laser / Gungmedia(Chungnam National University Press)
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