지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Hyaluronic acid(HA) microbeads were synthesized by dropping the sodium hyaluronate(Streptococcus)solutions in NaOH into a solution mixture of divinyl sulfone(DVS) in 2-methyl-1-propanol, followed by stirring, cleaning and drying process at room temperature. The initial experimental conditions are crosslinking time(CLTi) of 5 h,crosslinking temperature(CLTe) of room temperature, injection air pressure(IAPr) of 5 psi, and DVS concentration(DVSc) of 0.2 vol%, respectively. Then, parametric studies were performed by varying the parameters to investigate the morphology, the porosity, the swelling ratio and the size of the beads. The microbead size pattern was not regular to function of the degree of crosslink. It was observed that the swelling ratio, the degree of crosslink, and the pore size can be controlled by adjusting the CLTi, CLTe and DVSc. Among the parameters investigated, the smallest bead size can be achieved by varying the CLTi parameter. The lowest swelling ratio, as an indication of the highest degree of crosslink, can be obtained by varying CLTe.
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참고문헌 (28)
참고문헌 신청
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A. Pourjavadi / 2008 / Taguchi optimized synthesis of collagen-g-poly(acrylic acid)/kaolin composite superabsorbent hydrogel / European Polymer Journal 44 : 1209 ~ 1216
A.M. Afify / 1993 / Purification and characterization of human serum hyaluronidase / Biochem Biophys 305 (2) : 434 ~ 441
/ / Microbead of hyaluronic acid derivatives for medical purpose and process for preparing the same
/ / Microbeads of natural polysaccharide and hyaluronic acid and processes for preparing the same
A. Pourjavadi / 2008 / Taguchi optimized synthesis of collagen-g-poly(acrylic acid)/kaolin composite superabsorbent hydrogel / European Polymer Journal 44 : 1209 ~ 1216
A.M. Afify / 1993 / Purification and characterization of human serum hyaluronidase / Biochem Biophys 305 (2) : 434 ~ 441
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