지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: To examine the association between alcohol consumption habit, types of beverages, alcohol consumption quantity, and overall and cancer-specific mortality among Korean adults.
Methods: The alcohol consumption information of a total of 16 320 participants who were 20 years or older from the Korean Multicenter Cancer Cohort were analyzed to examine the association between alcohol consumption habit and mortality (median follow-up of 9.3 years). The Cox proportional hazard model was used to estimate the hazard ratio (HR) of alcohol consumption to mortality adjusting for age, sex, geographic areas, education, smoking status, and body mass index.
Results: Alcohol drinkers showed an increased risk for total mortality compared with never drinkers (HR, 1.72; 95% confidence interval [CI], 1.38 to 2.14 for past drinkers; HR, 1.21; 95% CI, 1.06 to 1.39 for current drinkers), while past drinkers only were associated with higher risk for cancer deaths (HR, 1.84; 95% CI, 1.34 to 2.53). The quantity of alcohol consumed per week showed a J-shaped association with risk of mortality. Relative to light drinkers (0.01 to 90 g/wk), never drinkers and heavy drinkers ( >504 g/wk) had an increased risk for all-cause and cancer deaths: (HR, 1.18; 95% CI, 0.96 to 1.45) and (HR, 1.39; 95% CI, 1.05 to 1.83) for all-cause mortality; and (HR,1.55; 95% CI, 1.15 to 2.11) and (HR, 2.07; 95% CI, 1.39 to 3.09) for all cancer mortality, respectively. Heavy drinkers (>504 g/wk) showed an elevated risk for death from stomach and liver cancers.
Conclusions: The present study supports the existence of a J-shaped association between alcohol consumption quantity and the risk of all-cause and cancer deaths. Heavy drinkers had an increased risk of death from cancer overall and liver and stomach cancer.
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참고문헌 (24)
참고문헌 신청
Bandera EV / 2001 / Alcohol consumption and lung cancer: a review of the epidemiologic evidence / Cancer Epidemiol Biomarkers Prev 10 (8) : 813 ~ 821
Bongaerts BW / 2008 / Alcohol consumption, type of alcoholic beverage and risk of colorectal cancer at specific subsites / Int J Cancer 123 (10) : 2411 ~ 2417
Chao C / 2011 / Alcohol consumption and risk of lung cancer in the VITamins And Lifestyle Study / Nutr Cancer 63 (6) : 880 ~ 888
Fan AZ / 2006 / Lifetime alcohol drinking pattern is related to the prevalence of metabolic syndrome. The Western New York Health Study (WNYHS) / Eur J Epidemiol 21 (2) : 129
Fan Y / 2008 / Alcohol, tobacco, and diet in relation to esophageal cancer: the Shanghai Cohort Study / Nutr Cancer 60 (3) : 354 ~ 363
Bongaerts BW / 2008 / Alcohol consumption, type of alcoholic beverage and risk of colorectal cancer at specific subsites / Int J Cancer 123 (10) : 2411 ~ 2417
Chao C / 2011 / Alcohol consumption and risk of lung cancer in the VITamins And Lifestyle Study / Nutr Cancer 63 (6) : 880 ~ 888
Fan AZ / 2006 / Lifetime alcohol drinking pattern is related to the prevalence of metabolic syndrome. The Western New York Health Study (WNYHS) / Eur J Epidemiol 21 (2) : 129
Fan Y / 2008 / Alcohol, tobacco, and diet in relation to esophageal cancer: the Shanghai Cohort Study / Nutr Cancer 60 (3) : 354 ~ 363
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