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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: Smoking is known to be associated with nephropathy in patients with diabetes. The distinct effects of smoking before and after diabetes has been diagnosed, however, are not well characterized. We evaluated the association of cigarette smoking before and after a diagnosis of diabetes with the presence of diabetic nephropathy.
Methods: We analyzed data from the 2011-2013 editions of the Korea National Health and Nutrition Examination Survey. A total of 629 male patients diagnosed with diabetes were classified as non-smokers (90 patients), former smokers (225 patients), or continuing smokers (314 patients). A “former smoker” was a patient who smoked only before receiving his diagnosis of diabetes. A “continuing smoker” was a patient who smoked at any time after his diabetes had been diagnosed. Diabetic nephropathy was defined as the presence of albuminuria (spot urine albumin/creatinine ratio ≥30 mg/g) or low estimated glomerular filtration rate (<60 mL/min/1.73 m2). Multiple logistic regression models were used to assess the independent association after adjusting for age, duration of diabetes, hemoglobin A1c, body mass index, systolic blood pressure, medication for hypertension, and medication for dyslipidemia. Female patients were excluded from the study due to the small proportion of females in the survey who smoked.
Results: Compared to non-smokers, continuing smokers had significantly higher odds ratio ([OR], 2.17; 95% confidence interval [CI], 1.23 to 3.83) of suffering from diabetic nephropathy. The corresponding OR (95% CI) for former smokers was 1.26 (0.70 to 2.29).
Conclusions: Smoking after diagnosis of diabetes is significantly associated with the presence of diabetic nephropathy in the Korean male population.
목차
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참고문헌 (37)
참고문헌 신청
안재희 / 2014 / Prevalence and Determinants of Diabetic Nephropathy in Korea: Korea National Health and Nutrition Examination Survey / Diabetes and Metabolism Journal 38(2):109~119
de Boer IH / 2009 / Cystatin C, albuminuria, and mortality among older adults with diabetes / Diabetes Care 32(10):1833~1838
Gerstein HC / 2001 / Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals / JAMA 286(4):421~426
Molitch ME / 2004 / Nephropathy in diabetes / Diabetes Care 27(Suppl 1):S79~S83
진동찬 / 2015 / Major changes and improvements of dialysis therapy in Korea: review of end-stage renal disease registry / The Korean Journal of Internal Medicine 30(1):17~22
de Boer IH / 2009 / Cystatin C, albuminuria, and mortality among older adults with diabetes / Diabetes Care 32(10):1833~1838
Gerstein HC / 2001 / Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals / JAMA 286(4):421~426
Molitch ME / 2004 / Nephropathy in diabetes / Diabetes Care 27(Suppl 1):S79~S83
진동찬 / 2015 / Major changes and improvements of dialysis therapy in Korea: review of end-stage renal disease registry / The Korean Journal of Internal Medicine 30(1):17~22
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