지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 223 - 233 (11page)
이용수
초록· 키워드
오류제보하기
PurposeThis study was conducted in order to determine the most cost-effective strategy, interms of interval and age range, for liver cancer screening in the high-risk populationof Korea.
Materials and MethodsA stochastic model was used to simulate the cost-effectiveness of liver cancer screeningby combined ultrasonography and alpha-fetoprotein testing when varying bothscreening intervals and age ranges. The effectiveness of these screening strategiesin the high-risk population was defined as the probability of detecting preclinical livercancer, and cost was based on the direct cost of the screening and confirmative tests.
Optimal cost-effectiveness was determined using the incremental cost-effectivenessratio.
ResultsAmong the 36 alternative strategies, one-year or two-year interval screening for menaged between 50 and 80 years, six-month or one-year interval screening for menaged between 40 and 80 years, and six-month interval screening for men agedbetween 30 and 80 years were identified as non-dominated strategies. For women,identified non-dominated strategies were: one-year interval screening between age50 and 65 years, one-year or six-month interval screening between age 50 and 80years, six-month interval screening between age 40 and 80 years, and six-monthinterval screening between age 30 and 80 years.
ConclusionIn Korea, a one-year screening interval for men aged 50 to 80 years would bemarginally cost-effective. Further studies should be conducted in order to evaluateeffectiveness of liver cancer screening, and compare the cost effectiveness of differentliver cancer screening programs with a final outcome indicator such as qualityadjustedlife-years or disability-adjusted life-years.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
/ 2010 / Asia-Pacific Working Party on Prevention of Hepatocellular Carcinoma. Prevention of hepatocellular carcinoma in the Asia-Pacific region: consensus statements / J Ga
Bolondi L / 2001 / Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma : a cost effectiveness analysis / Gut 48 : 251 ~
Bruix J / 2001 / Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver / J Hepa
Chen TH / 2002 / Ultrasound screening and risk factors for death from hepatocellular carcinoma in a high risk group in Taiwan / Int J Cancer 98 : 257 ~ 261
Daniele B / 2004 / Alfa fetoprotein and ultrasonography screening. Hepatocellular carcinoma screening, diagnosis, and management : 69 ~ 73
Bolondi L / 2001 / Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma : a cost effectiveness analysis / Gut 48 : 251 ~
Bruix J / 2001 / Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver / J Hepa
Chen TH / 2002 / Ultrasound screening and risk factors for death from hepatocellular carcinoma in a high risk group in Taiwan / Int J Cancer 98 : 257 ~ 261
Daniele B / 2004 / Alfa fetoprotein and ultrasonography screening. Hepatocellular carcinoma screening, diagnosis, and management : 69 ~ 73
이 논문의 저자 정보
최근 본 자료
댓글(0)
0