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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 118 - 128 (11page)
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Purpose Although Korea has the highest incidence of gastric cancer worldwide and D2-lymphadenectomies are routinely performed, radiotherapy (RT) practice patterns have not been well studied. Therefore, we examined RT usage trends for neoadjuvant/adjuvant patients and identified factors associated with RT. We also examined survival benefits and net medical cost advantages of adding RT. Materials and Methods Patients diagnosed with gastric cancer who underwent gastrectomy from 2002-2013 were identified using National Health Insurance Service-National Sample Cohort. Results Annually, 30.9 cases per 100,000 population in crude rate underwent gastrectomy in 230 hospitals and 49.8% received neoadjuvant/adjuvant therapy in 182 hospitals. For neoadjuvant/ adjuvant patients, postoperative chemo-RT was administered in 4% of cases in 26 hospitals. No significant trends regarding treatment type were observed over time. Having undergone RT was inversely associated with being ! 60 years old and having a low income. Having undergone RT was positively related to having a Charlson comorbidity index ! 4, hospital location and hospital volume (! 2,000 beds). Significant portions of patients treated with RT in this nation (52%) were concentrated in one large-volume hospital. Use of RT linked to increased cost of primary treatment, yet not to reduced overall medical expense. RT did not influence both on overall and disease-specific survivals after adjusting for potential confounders (p > 0.05). Conclusion RT was uncommonly utilized as adjuvant or neoadjuvant treatment by physicians in Korea. Despite intrinsic drawback in this data, we did not find either survival benefit or net medical cost advantage by adding RT in adjuvant treatment.
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참고문헌 (30)
참고문헌 신청
Torre LA / 2015 / Global cancer statistics, 2012 / CA Cancer J Clin 65:87~108
Colquhoun A / 2015 / Global patterns of cardia and non-cardia gastric cancer incidence in 2012 / Gut 64:1881~1888
정규원 / 2015 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2012 / Cancer Research and Treatment 47(2):127~141
Lim DH / 2004 / Patterns of failure in gastric carcinoma after D2 gastrectomy and chemoradiotherapy: a radiation oncologist's view / Br J Cancer 91:11~17
Knight G / 2013 / Neoadjuvant or adjuvant therapy for resectable gastric cancer: a systematic review and practice guideline for North America / Gastric Cancer 16:28~40
Colquhoun A / 2015 / Global patterns of cardia and non-cardia gastric cancer incidence in 2012 / Gut 64:1881~1888
정규원 / 2015 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2012 / Cancer Research and Treatment 47(2):127~141
Lim DH / 2004 / Patterns of failure in gastric carcinoma after D2 gastrectomy and chemoradiotherapy: a radiation oncologist's view / Br J Cancer 91:11~17
Knight G / 2013 / Neoadjuvant or adjuvant therapy for resectable gastric cancer: a systematic review and practice guideline for North America / Gastric Cancer 16:28~40
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