지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 121 - 130 (10page)
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초록· 키워드
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Objective Decreased cardiac vagal control (CVC) has been proposed in posttraumatic stress disorder (PTSD), but the results are mixed. Analyses with larger sample sizes and better methodology are needed.
Methods Thirty-two drug-naïve survivors with current PTSD, 32 survivors without PTSD and 192 matched controls were recruited for a case-control analysis. We used the PTSD checklist-civilian version (PCL-C) to assess posttraumatic symptoms severity. Cardiac autonomic function was evaluated by measuring heart rate variability (HRV) parameters. Frequency-domain indices of HRV were obtained. The obtained results were evaluated in association with personality traits assessed by the Tridimensional Personality Questionnaire (TPQ).
Results PTSD patients exhibited decreased LF-HRV and HF-HRV as compared to survivors without PTSD and to matched controls. The PTSD symptoms severity was associated with reduced mean RR intervals, Var-HRV, LF-HRV and HF-HRV. The harm avoidance score (which has been suggested to be associated with serotonergic activity) was negatively correlated with Var-HRV, LF-HRV and HF-HRV.
Conclusion These data suggest that PTSD is accompanied by decreased CVC, highlighting the importance of assessing HRV in PTSD patients. In view of the increased risk for cardiovascular diseases in these vulnerable individuals, one might consider the treatment to restore their autonomic function while reducing PTSD symptoms.
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참고문헌 (22)
참고문헌 신청
/ 1996 / Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North Ameri
Ballenger JC / 2000 / Consensus statement on posttraumatic stress disorder from the International Consensus Group on Depression and Anxiety / J Clin Psychiatry 61 (Suppl 5)
Byoung-A Song / 2011 / Post-Traumatic Stress Disorder, Depression, and Heart-Rate Variability among North Korean Defectors / PSYCHIATRY INVESTIGATION 8 (4) : 297 ~ 304
Chang CC / 2007 / Lack of association between the norepinephrine transporter gene and major depression in a Han Chinese population / J Psychiatry Neurosci 32 : 121 ~ 128
Cohen H / 1997 / Power spectral analysis of heart rate variability in posttraumatic stress disorder patients / Biol Psychiatry 41 : 627 ~ 629
Ballenger JC / 2000 / Consensus statement on posttraumatic stress disorder from the International Consensus Group on Depression and Anxiety / J Clin Psychiatry 61 (Suppl 5)
Byoung-A Song / 2011 / Post-Traumatic Stress Disorder, Depression, and Heart-Rate Variability among North Korean Defectors / PSYCHIATRY INVESTIGATION 8 (4) : 297 ~ 304
Chang CC / 2007 / Lack of association between the norepinephrine transporter gene and major depression in a Han Chinese population / J Psychiatry Neurosci 32 : 121 ~ 128
Cohen H / 1997 / Power spectral analysis of heart rate variability in posttraumatic stress disorder patients / Biol Psychiatry 41 : 627 ~ 629
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