지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives The purpose of this study was to investigate the prevalence and clinical characteristics of Wernicke’s encephalopathy (WE) patients in alcoholics and to evaluate the utility of Caine’s criteria as a screening test.
Methods We made an admission note including Caine’s criteria and applied it to patients who were admitted to an alcohol treatment unit. Demographic, clinical, and laboratory data were collected on 204 alcoholics. Our alcoholics who met more than one of Caine’s criteria were considered at risk for WE and were given high-dose thiamine IV therapy.
Results WE was diagnosed in 15.2% of the alcoholic patients. Age and head trauma history were risk factors of WE. The sensitivity of Caine’s criteria was 97% and specificity was 54%. High-dose thiamine IV therapy appeared to be a safe and cost-effective method to prevent the serious complications of WE.
Conclusion Caine’s criteria is useful as a screening test for WE among alcoholic patients. High-dose thiamine IV therapy is cost-effective for alcoholic patients who are considered to be at risk for WE.
목차
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참고문헌 (18)
참고문헌 신청
/ 2010 / Restoration of mammillothalamic functional connectivity through thiamine replacement therapy in Wernicke's encephalopathy / Neuroscience Letters 479 (3) : 257 ~ 261
Antunez E / 1998 / Usefulness of CT and MR imaging in the diagnosis of acute Wernicke’s encephalopathy / AJR Am J Roentgenol 171 : 1131 ~ 1137
Bagby RM / 2004 / The Hamilton Depression Rating Scale: has the gold standard become a lead weight / Am J Psychiatry 161 : 2163 ~ 2177
Brion S / 2001 / Post-traumatic Korsakoff’s syndrome: clinical and anatomical report / Encephale 27 : 513 ~ 525
Caine D / 1997 / Operational criteria for the classification of chronic alcoholics: identification of Wernicke’s encephalopathy / J Neurol Neurosurg Psychiatry 62 : 51 ~ 60
Antunez E / 1998 / Usefulness of CT and MR imaging in the diagnosis of acute Wernicke’s encephalopathy / AJR Am J Roentgenol 171 : 1131 ~ 1137
Bagby RM / 2004 / The Hamilton Depression Rating Scale: has the gold standard become a lead weight / Am J Psychiatry 161 : 2163 ~ 2177
Brion S / 2001 / Post-traumatic Korsakoff’s syndrome: clinical and anatomical report / Encephale 27 : 513 ~ 525
Caine D / 1997 / Operational criteria for the classification of chronic alcoholics: identification of Wernicke’s encephalopathy / J Neurol Neurosurg Psychiatry 62 : 51 ~ 60
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