지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 349 - 359 (11page)
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초록· 키워드
오류제보하기
ObjectiveaaHealthy individuals show stronger gamma-band activities (GBAs) for socially relevant stimuli (human faces) than for non-relevant ones. This study aimed to examine whether this gamma-band preference occurs in patients with schizophrenia.
MethodsaaEEG was recorded for 24 patients with schizophrenia and 23 healthy controls while they viewed pictures of human faces, chairs, and nature scenes. The spectral powers of high-beta (20–30 Hz) and gamma (30–80 Hz) frequencies were analyzed along 3 midline cortical regions, and phase synchronization was calculated.
ResultsaaCompared to the response to non-facial stimuli, higher event related deactivation to facial stimuli was observed for the high-beta frequency across groups. For the gamma frequency, early-stage GBA was increased and late-stage GBA was decreased for all 3 stimuli in patients with schizophrenia compared to healthy controls. Preferential GBA patterns (100–200 and 200–300 ms) were found in healthy controls, but not in patients with schizophrenia. Significant correlation existed between negative symptoms and GBA in the frontal region for chair and scene stimuli. There was no significant intergroup difference in phase synchronization pattern.
ConclusionaaOur results suggest that patients with schizophrenia have deficits in the preferential pattern of GBA for human faces and the deficits in the preferential pattern were mainly influenced by over-response to socially non-relevant stimuli.
목차
등록된 정보가 없습니다.
참고문헌 (49)
참고문헌 신청
Zion-Golumbic E / 2008 / Human face preference in gamma-frequency EEG activity / Neuroimage 39:1980~1987
Uhlhaas PJ / 2011 / A new look at gamma? High- (>60 Hz) gamma-band activity in cortical networks:function, mechanisms and impairment / Prog Biophys Mol Biol 105:14~28
Salinas E / 2001 / Correlated neuronal activity and the flow of neural information / Nat Rev Neurosci 2:539~550
Tallon-Baudry C / 1999 / Oscillatory gamma activity in humans and its role in object representation / Trends Cogn Sci 3:151~162
Fries P / 2001 / Modulation of oscillatory neuronal synchronization by selective visual attention / Science 291:1560~1563
Uhlhaas PJ / 2011 / A new look at gamma? High- (>60 Hz) gamma-band activity in cortical networks:function, mechanisms and impairment / Prog Biophys Mol Biol 105:14~28
Salinas E / 2001 / Correlated neuronal activity and the flow of neural information / Nat Rev Neurosci 2:539~550
Tallon-Baudry C / 1999 / Oscillatory gamma activity in humans and its role in object representation / Trends Cogn Sci 3:151~162
Fries P / 2001 / Modulation of oscillatory neuronal synchronization by selective visual attention / Science 291:1560~1563
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