지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 173 - 178 (6page)
이용수
초록· 키워드
오류제보하기
Objective Cigarette smoking is associated with a variety of health problems including cardiovascular, pulmonary, neoplasms, endocrinopathies including diabetes, the metabolic syndrome, and chronic inflammation. Adiponectin is an adipocyte-derived plasma protein that is closely associated with insulin sensitivity and the metabolic syndrome. The aim of this study was to evaluate the changes of plasma adiponectin levels after smoking cessation.
Methods Thirty seven smokers that wanted to stop smoking without any nicotine replacement therapy or medication were recruited for this study. Fifteen smokers succeeded in stopping smoking (validated by urine cotinine levels ≤50 ng/mL) and 22 smokers failed. Therefore, only the 15 that succeeded were included in the analysis. The plasma adiponectin levels were determined using a commercially available enzyme-linked immunosorbent assay.
Results The mean age of the successful 15 was 35±9.3 years old. They were all males. The daily smoking habit was a mean of 13.5±5.4 cigarettes per day. The mean Nicotine Dependence Syndrome Scale (NDSS) and Fagerstrom Test for Nicotine Dependence (FTND) scores were 55.6±9.6 and 2.9±1.9. During the study period of three months, the mean body mass index (BMI), body fat mass (BFM), waist-hip ratio (WHR) and body weight increased by 1.1 kg/m2, 3.0%, 0.02%, and 2.9 kg, respectively. The baseline mean adiponectin level in the subjects was 11.9±5.2 mg/L. The mean adiponectin levels measured at one and three months were 16.0±5.1 mg/L and 14.7±4.5 mg/L respectively. The mean plasma adiponectin levels of the successful group was significantly increased after four weeks when compared to the baseline (z=-2.401, p=0.016). However, the decrease in plasma adiponectin levels at one and three months was not statistically significant.
Conclusion Even though the decrease over the next two months was not significant, these findings, the increase of plasma level of adiponectin after smoking cessation, provide preliminary data for future research on the possible mechanisms associated with smoking cessation and changes in body metabolism.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Abbasi F / 2006 / The relationship between plasma adiponectin concentration and insulin resistance is altered in smokers / J Clin Endocrinol Metab 91 : 5002 ~ 5007
American Psychiatric Association / 1994 / Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition / American Psychiatric Association
Bamia C / 2004 / Tobacco smoking in relation to body fat mass and distribution in a general population sample / Int J Obes Relat Metab Disord 28 : 1091 ~ 1096
Beltowski J / 2008 / Adiponectin and its role in cardiovascular diseases / Cardiovasc Hematol Disord Drug Targets 8 : 7 ~ 46
Canoy D / 2005 / Cigarette smoking and fat distribution in 21,828 British men and women: a population-based study / Obes Res 13 : 1466 ~ 1475
American Psychiatric Association / 1994 / Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition / American Psychiatric Association
Bamia C / 2004 / Tobacco smoking in relation to body fat mass and distribution in a general population sample / Int J Obes Relat Metab Disord 28 : 1091 ~ 1096
Beltowski J / 2008 / Adiponectin and its role in cardiovascular diseases / Cardiovasc Hematol Disord Drug Targets 8 : 7 ~ 46
Canoy D / 2005 / Cigarette smoking and fat distribution in 21,828 British men and women: a population-based study / Obes Res 13 : 1466 ~ 1475
이 논문의 저자 정보
최근 본 자료
댓글(0)
0