지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 164 - 167 (4page)
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초록· 키워드
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Background Carotid cavernous fistula (CCF) is an abnormal communication between the carotid artery and the cavernous sinus. The pathogenesis of spontaneous CCF remains unclear,although sinus thrombosis is known to be a predisposing factor for dural arteriovenous fistula.
Because spontaneous CCFs are mainly of the dural type, we considered that thrombogenic conditions, such as, protein S deficiency might be associated with CCF.
Case Report A 42-year-old woman complained of conjunctival injection and retro-orbital pain that first appeared 1-month before visiting our hospital. She had no history of head trauma or intracranial surgery. Exophthalmos and chemosis were observed in her left eye, which also had lower visual acuity and higher intraocular pressure than the right eye. Magnetic resonance images and cerebral angiography revealed a left dural CCF. Her protein S was low, at 41%(normal range: 70-140%), but other hematologic values related to coagulation were normal.
Her symptoms were relieved after initial transvenous coil embolization. However, a newly developed sixth-nerve palsy was detected 4 days after initial embolization. Follow-up angiography revealed a minimal shunt, and thus transvenous coil embolization was repeated. Two days later, the ophthalmoplegia started reducing, and 1-month later it had almost disappeared.
Conclusions To the best of our knowledge, this is the first report of spontaneous dural CCF in a Korean patient with concurrent protein S deficiency. Interestingly, transient sixth-nerve palsy developed after transvenous coil embolization in this patient. This additional symptom caused by the residual fistula was relieved after additional transarterial embolization.
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참고문헌 (20)
참고문헌 신청
Aminoff MJ / 1973 / Vascular anomalies in the intracranial dura mater / Brain 96 : 601 ~ 612
Barrow DL / 1985 / Classification and treatment of spontaneous carotid-cavernous sinus fistulas / J Neurosurg 62 : 248 ~ 256
Castoldi E / 2008 / Regulation of coagulation by protein S / Curr Opin Hematol 15 : 529 ~ 536
Comp PC / 1984 / Recurrent venous thromboembolism in patients with a partial deficiency of protein S / N Engl J Med 311 : 1525 ~ 1528
Dykes AC / 2001 / A study of Protein S antigen levels in 3788 healthy volunteers: influence of age, sex and hormone use, and estimate for prevalence of deficiency state / Br
Barrow DL / 1985 / Classification and treatment of spontaneous carotid-cavernous sinus fistulas / J Neurosurg 62 : 248 ~ 256
Castoldi E / 2008 / Regulation of coagulation by protein S / Curr Opin Hematol 15 : 529 ~ 536
Comp PC / 1984 / Recurrent venous thromboembolism in patients with a partial deficiency of protein S / N Engl J Med 311 : 1525 ~ 1528
Dykes AC / 2001 / A study of Protein S antigen levels in 3788 healthy volunteers: influence of age, sex and hormone use, and estimate for prevalence of deficiency state / Br
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