지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 109 - 114 (6page)
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초록· 키워드
오류제보하기
Stroke is a prototype disorder that disables as well as kills people. The disability-adjusted life years (DALY) metric developed by the World Health Organization to measure the global burden of disease integrates healthy life years lost due to both premature mortality and living with disability. Accordingly, it is well suited to stroke research. The DALY has previously been applied only to large but relatively crude population-level data analyses, but now it is possible to calculate the DALY lost in individual stroke patients. Measuring each patient’s stroke outcome with DALY lost has expanded its application to the analysis of treatment effect in acute stroke trials, delineating the poststroke complication impact, the differential weighting of discrete vascular events, and estimating a more refined stroke burden in a specific population. The DALY metric has several advantages over conventional stroke outcome measures: 1) Since the DALY measures the burden of diverse health conditions with a common metric of life years lost, stroke burden and benefits of stroke interventions can be directly compared to other health conditions and their treatments. 2)Quantifying stroke burden or interventional benefits as the life years lost or gained makes the DALY metric more intuitively accessible for public and health system planners. 3) As a continuous, equal-interval scale, the DALY analysis might be statistically more powerful than either binary or ordinal rank outcome analyses in detecting the treatment effects of clinical trials. 4) While currently employed stroke outcome measures take one-time snapshots of disability or mortality and implicitly indicate long-term health impact, the DALY explicitly indicates the burdens of living with disability for an individual’s remaining life.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Bae HJ / 200511 / In-hospital medical complications and long-term mortality after ischemic stroke / STROKE 36 : 2441 ~ 2445
Brott TG / 2010 / Stenting versus endarterectomy for treatment of carotid-artery stenosis / N Engl J Med 363 : 11 ~ 23
Eriksson M / 2008 / Functional outcome 3 months after stroke predicts long-term survival / Cerebrovasc Dis 25 : 423 ~ 429
Ezzati M / 2003 / Comparative Risk Assessment Collaborating Group. Estimates of global and regional potential health gains from reducing multiple major risk factors / Lancet
Hacke W / 1998 / Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Au
Brott TG / 2010 / Stenting versus endarterectomy for treatment of carotid-artery stenosis / N Engl J Med 363 : 11 ~ 23
Eriksson M / 2008 / Functional outcome 3 months after stroke predicts long-term survival / Cerebrovasc Dis 25 : 423 ~ 429
Ezzati M / 2003 / Comparative Risk Assessment Collaborating Group. Estimates of global and regional potential health gains from reducing multiple major risk factors / Lancet
Hacke W / 1998 / Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Au
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