지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 401 - 406 (6page)
이용수
초록· 키워드
오류제보하기
Background and Purpose Antiganglioside antibodies are known to play a pathogenic role in Guillain-Barré syndrome (GBS). Either an immunoglobulin (Ig)G- or IgM-type anti-GM2 antibody is detected in rare cases in GBS patients. However, the specific pathogenic role of these antibodies in GBS has not been reported previously. This study aimed to define and characterize the clinical spectrum of GBS with anti-GM2 positivity. Methods We reviewed the database of the Dong-A University Neuroimmunology Team, which has collected sera of GBS and its variants from more than 40 general and universitybased hospitals in Korea. Detailed information about the involved patients was often obtained and then corrected by the charge doctor applying additional questionnaires. Results Four patients with acute monophasic peripheral neuropathy or cranial neuropathy with isolated IgM-type anti-GM2-antibody positivity were recruited. In addition, IgG-type anti-GM2 antibody was solely detected in the sera of another four patients. The IgM-positive group comprised heterogeneous syndromes: two cases of acute motor axonal neuropathy, one of acute inflammatory demyelinating polyneuropathy, and one of isolated facial diplegia. In contrast, all of the cases enrolled in the IgG-positive group manifested with dizziness with or without oculomotor palsy due to cranial neuropathy syndrome. Conclusions This study has identified that anti-GM2 antibody can be found in various subtypes of GBS and its variants in rare cases. Compared to the clinical heterogeneity of the IgMpositive group, the IgG-positive group can be characterized by cranial-dominant GBS variants presenting mainly with oculomotor and vestibular dysfunctions.
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Willison HJ / 2016 / Guillain-Barre syndrome / Lancet 388:717~727
Yuki N / 2012 / Guillain-Barre syndrome / N Engl J Med 366:2294~2304
Bae JS / 2014 / Guillain-Barre syndrome in Asia / J Neurol Neurosurg Psychiatry 85:907~913
Wakerley BR / 2014 / Guillain-Barre and Miller Fisher syndromes--new diagnostic classification / Nat Rev Neurol 10:537~544
Uncini A / 2012 / Electrodiagnostic criteria for Guillain-Barre syndrome: a critical revision and the need for an update / Clin Neurophysiol 123:1487~1495
Yuki N / 2012 / Guillain-Barre syndrome / N Engl J Med 366:2294~2304
Bae JS / 2014 / Guillain-Barre syndrome in Asia / J Neurol Neurosurg Psychiatry 85:907~913
Wakerley BR / 2014 / Guillain-Barre and Miller Fisher syndromes--new diagnostic classification / Nat Rev Neurol 10:537~544
Uncini A / 2012 / Electrodiagnostic criteria for Guillain-Barre syndrome: a critical revision and the need for an update / Clin Neurophysiol 123:1487~1495
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Atypical Asymmetric Guillain-Barre Syndrome Overlapping with Miller-Fisher Syndrome: A Case Report
대한근전도 전기진단의학회지
2021 .08
-
Distal acquired demyelinating symmetric neuropathy associated with anti-GM1 and anti-GD1b antibodies
Annals of Clinical Neurophysiology
2017 .01
-
Determining the Utility of the Guillain-Barre Syndrome Classification Criteria
Journal of Clinical Neurology
2021 .01
-
Electrognostic findings of Guillain-Barré syndrome
Annals of Clinical Neurophysiology
2020 .01
-
Overlap syndrome of Miller-Fisher syndrome/ Pharyngeal-Cervical-Brachial variant-Guillain Barre Syndrome with anti-ganglioside complex antibodies
Annals of Clinical Neurophysiology
2020 .01
-
Acute unilateral isolated abducens nerve palsy associated with anti-GM1 immunoglobulin M antibody
Annals of Clinical Neurophysiology
2019 .01
-
Finger Drop-Dominant Variant of Guillain-Barre Syndrome in a Patient With COVID-19: A Case Report
Journal of Korean Medical Science
2022 .05
-
만성적 경과관찰을 보이는 Guillain-Barré Syndrome 환자 1례
대한한방내과학회지
2018 .01
-
Early Electrodiagnostic Features of Upper Extremity Sensory Nerves Can Differentiate Axonal Guillain-Barré Syndrome from Acute Inflammatory Demyelinating Polyneuropathy
Journal of Clinical Neurology
2016 .01
-
Relationship between GB stone and GB cancer : Optimum time of treatment
한국간담췌외과학회 학술대회지
2016 .04
-
Clinical Features of Post-Vaccination Guillain-Barré Syndrome (GBS) in Korea
Journal of Korean Medical Science
2017 .01
-
Epidemiological Features and Economic Burden of Guillain-Barre Syndrome in South Korea: A Nationwide Population-Based Study
Journal of Clinical Neurology
2021 .01
-
Guillain–Barré Syndrome After COVID-19 Infection in Korea: A Case Series
Journal of Korean Medical Science
2024 .02
-
Anti-H Antibody Showing Agglutination in the Anti-Human Globulin Phase in a Korean Patient
Annals of Laboratory Medicine
2016 .01
-
승령(GB18) 혈위와 취혈 방법에 대한 고찰
Korean Journal of Acupuncture
2018 .01
-
Status of group B streptococcal CROSSMARK_logo_3_Test 1 / 1 vaccine development
Clinical and Experimental Vaccine Research
2018 .01
-
Recurrent Guillain-Barré Syndrome with Anti-GT1a and Anti-GQ1b Ganglioside Antibodies
Journal of Clinical Neurology
2019 .01
-
A Case of Postoperative Guillain-Barré Syndrome After Nasal Surgery
Journal of Rhinology
2023 .03
-
Prediction of Functional Outcome in Axonal Guillain-Barre Syndrome
Annals of Rehabilitation Medicine
2016 .01
-
SARS-CoV-2 항체 검사를 위한 뉴클레오캡시드 단백질 항원을 이용한 ELISA의 분석적, 임상적 성능 평가
Laboratory Medicine Online
2021 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0