지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 166 - 171 (6page)
이용수
초록· 키워드
오류제보하기
Background and Purpose We compared the motor-unit number estimation (MUNE) findings in patients who presented with signs and/or findings associated with carpal tunnel syndrome (CTS) and healthy controls, with the aim of determining if motor-unit loss occurs during the clinically silent period and if there is a correlation between clinical and MUNE findings in CTS patients.
Methods The study investigated 60 hands of 35 patients with clinical CTS and 60 hands of 34 healthy controls. Routine median and ulnar nerve conduction studies and MUNE analysis according to the multipoint stimulation method were performed.
Results The most common electrophysiological abnormality was reduced conduction velocity in the median sensory nerve (100% of the hands). The MUNE value was significantly lower for the patient group than for the control group (p=0.0001). ROC analysis showed that a MUNE value of 121 was the optimal cutoff for differentiating between patients and controls, with a sensitivity of 63.3% and a specificity of 68.3%. MUNE values were lower in patients with complaints of numbness, pain, and weakness in the median nerve territory (p<0.05, for all comparisons), and lower in patients with hypoesthesia than in patients with normal neurological findings (p=0.023).
Conclusions The MUNE technique is sensitive in detecting motor nerve involvement in CTS patients who present with sensorial findings, and it may be useful in detecting the loss of motor units during the early stages of CTS. Larger-scale prospective clinical trials assessing the effect of early intervention on the outcome of these patients would help in confirming the possible benefit of detecting subclinical motor-unit loss in CTS.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Katz JN / 2002 / Clinical practice. Carpal tunnel syndrome / N Engl J Med 346:1807~1812
Omer GE Jr / 1992 / Median nerve compression at the wrist / Hand Clin 8:317~324
Stevens JC / 1997 / AAEM minimonograph #26: the electrodiagnosis of carpal tunnel syndrome. American Association of Electrodiagnostic Medicine / Muscle Nerve 20:1477~1486
Jablecki CK / 2002 / Practice parameter: electrodiagnostic studies in carpal tunnel syndrome. Report of the American Association of Electrodiagnostic Medicine, American Academy of Neurology, and the American Academy of Physical Medicine and Rehabilitation / Neurology 58:1589~1592
McComas AJ / 1971 / Electrophysiological estimation of the number of motor units within a human muscle / J Neurol Neurosurg Psychiatry 34:121~131
Omer GE Jr / 1992 / Median nerve compression at the wrist / Hand Clin 8:317~324
Stevens JC / 1997 / AAEM minimonograph #26: the electrodiagnosis of carpal tunnel syndrome. American Association of Electrodiagnostic Medicine / Muscle Nerve 20:1477~1486
Jablecki CK / 2002 / Practice parameter: electrodiagnostic studies in carpal tunnel syndrome. Report of the American Association of Electrodiagnostic Medicine, American Academy of Neurology, and the American Academy of Physical Medicine and Rehabilitation / Neurology 58:1589~1592
McComas AJ / 1971 / Electrophysiological estimation of the number of motor units within a human muscle / J Neurol Neurosurg Psychiatry 34:121~131
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