지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 34 - 39 (6page)
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초록· 키워드
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Background and Purpose:Guillain-Barré syndrome (GBS) is an acute demyelinating polyneuropathy with various clinical features. Optic neuritis occurs in rare cases. In this study we determined the incidence and patterns of visual evoked potential (VEP) abnormality in GBS in association with ophthalmologic findings.
Methods:Thirty-two patients with a diagnosis of GBS were included in the study. The correlation between pathologic VEPs and categories of neurologic deficit and electrophysiological findings were examined statistically.
Results:The patients ranged in age from 19 to 77 years. Five cases (16%) had abnormal VEPs.
All five of these patients exhibited increased P100 latency differences between the two eyes. Other abnormalities were prolonged p100 latency, increased interocular amplitude difference, and distorted p100 configuration. Pathologic signs on ophthalmologic examination were observed in 80% of patients with abnormal VEPs. VEP abnormality was never present in pure axonal forms.
There was no significant correlation between pathologic VEP and cerebrospinal fluid protein level or categories of neurologic deficits.
Conclusions:Involvement of the optic pathways is not a frequent finding in GBS. When present it is always asymmetric and generally accompanied with pathologic findings on ophthalmologic examination. VEPs may be abnormal in different clinical variants of GBS, and especially in demyelinating forms.
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참고문헌 (25)
참고문헌 신청
Asbury AK / 1990 / Assessment of current diagnostic criteria for Guillain-Barre syndrome / Ann Neurol 27 (Suppl) : 21 ~ 24
Behan PO / 1976 / Optic neuritis in the Landry-Guillain-Barre-Strohl syndrome / Br J Ophthalmol 60 : 58 ~ 59
Caccavale A / 2000 / Acute onset of a bilateral areflexical mydriasis in Miller-Fisher syndrome: a rare neuro-ophthalmologic disease / J Neuroophthalmol 20 : 61 ~ 62
Chan JW / 2003 / Optic neuritis in anti-GQ1b positive recurrent Miller Fisher syndrome / Br J Ophthalmol 87 : 1185 ~ 1186
Delisa JA / 1994 / Auditory and visual evoked potentials in: Manual of nerve conduction velocity and clinical neurophysiology / Lippincott Williams and Wilkins : 294 ~ 304
Behan PO / 1976 / Optic neuritis in the Landry-Guillain-Barre-Strohl syndrome / Br J Ophthalmol 60 : 58 ~ 59
Caccavale A / 2000 / Acute onset of a bilateral areflexical mydriasis in Miller-Fisher syndrome: a rare neuro-ophthalmologic disease / J Neuroophthalmol 20 : 61 ~ 62
Chan JW / 2003 / Optic neuritis in anti-GQ1b positive recurrent Miller Fisher syndrome / Br J Ophthalmol 87 : 1185 ~ 1186
Delisa JA / 1994 / Auditory and visual evoked potentials in: Manual of nerve conduction velocity and clinical neurophysiology / Lippincott Williams and Wilkins : 294 ~ 304
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