지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 146 - 150 (5page)
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초록· 키워드
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Background and Purpose The present study was designed to investigate whether 24 h of SD negatively affects the attention and working memory and increases the serum concentrations of stress hormones, glucose, and inflammatory markers.
Methods The acute effects of sleep deprivation (SD) on cognition and the stress hormones were evaluated in six healthy volunteers (all men, age 23-27 years). All were good sleepers, had no history of medical or neuropsychiatric diseases, and were not taking any kind of medication. All of the volunteers were subjected to the Continuous Performance Test (CPT) for attention and working memory of cognition and blood tests both before and after 24 h of SD. Electroencephalographic monitoring was performed during the study to confirm the wakefulness of the subjects.
Results SD significantly elevated the serum concentrations of stress hormones (cortisol, epinephrine, and norepinephrine), but serum levels of glucose and inflammatory markers were not changed compared to baseline. For easier steps of the CPT the subjects performed well in giving correct responses after SD; the correct response scores decreased only at the most difficult step of the CPT. However, the subjects performed consistently poor for the error responses at all steps after SD. There was no correlation between the CPT scores and stress hormone levels.
Conclusions The 24 h of SD significantly heightened the levels of stress hormones and lowered attention and working memory. The acute SD condition seems to render the subject more susceptible to making errors.
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참고문헌 (22)
참고문헌 신청
Adam M / 2006 / Age-related changes in the time course of vigilant attention during 40 hours without sleep in men / Sleep 29 : 55 ~ 57
Altena E / 2010 / Reduced orbitofrontal and parietal gray matter in chronic insomnia: a voxel-based morphometric study / Biol Psychiatry 67 : 182 ~ 185
Conners CK / 2000 / Conners’ Continuous Performance Test II: Computer Program for Windows Technical Guide and Software Manual. North Tonawanda / Multi-Health Systems
Diamond DM / 1994 / Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats / Behav Brain Res 62 : 1 ~ 9
Frey DJ / 2007 / The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults / Brain Behav Immun 21 : 1050 ~ 1057
Altena E / 2010 / Reduced orbitofrontal and parietal gray matter in chronic insomnia: a voxel-based morphometric study / Biol Psychiatry 67 : 182 ~ 185
Conners CK / 2000 / Conners’ Continuous Performance Test II: Computer Program for Windows Technical Guide and Software Manual. North Tonawanda / Multi-Health Systems
Diamond DM / 1994 / Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats / Behav Brain Res 62 : 1 ~ 9
Frey DJ / 2007 / The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults / Brain Behav Immun 21 : 1050 ~ 1057
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