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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제3권 제2호
- 발행연도
- 2015.1
- 수록면
- 109 - 115 (7page)
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초록· 키워드
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Purpose: IgE is associated with allergic disease. However, insufficient research has been carried out regarding the levels of serum IgA in children with allergic disease. The purpose of this study was to evaluate the levels of serum immunoglobulin in Korean children with allergic disease and to identify significant correlations between such diseases and serum IgA levels.
Methods: We evaluated 338 children who visited the Pediatric Allergy Clinic, CHA Bundang Medical Center from March 2007 to July 2013. We assessed factors, such as sex, age, and family history of allergic diseases. Laboratory tests, including serum IgG, A, and M, total IgE, and specific IgE, were carried out on all patients. In addition, we compared serum IgA levels in allergic Korean children with normal reference ranges.
Results: The median (interquartile range) of serum IgA values was 31.1 mg/dL (14.3–50.6 mg/dL) in cases of food allergy and 44.3 mg/dL (25.7–94.2 mg/dL) in cases of atopic dermatitis. The serum IgA levels were lower in allergic Korean children aged 9–12 months and 25–72 months than in the normal mean reference values. Relationships between age and serum IgA levels were statistically significant in allergic children.
Conclusion: Our study suggests that serum IgA levels might be lower in allergic children than in the normal mean reference values. In order to understand this mechanism, normal levels for IgA in Korean children must be determined.
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등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Al-saimary IE / 2013 / Serum immunoglobulin and complement component levels in patients with atopic dermatitis / Adv Biores 4 : 111 ~
Anupama N / 2005 / The serum immunoglobulin E level reflects the severity of bronchial asthma / Thai J Physiol Sci 18 : 35 ~ 40
Bottcher MF / 2002 / Total and allergen-specific immunoglobulin A levels in saliva in relation to the development of allergy in infants up to 2 years of age / Clin Exp Aller
Fraser NG / 1969 / Immunoglobulins in dermatitis herpetiformis and various other skin diseases / Br J Dermatol 81 : 89 ~ 95
Gleeson M / 1996 / Development of bronchial hyperreactivity following transient absence of salivary IgA / Am J Respir Crit Care Med 153 (6 Pt 1) : 1785 ~ 1789
Anupama N / 2005 / The serum immunoglobulin E level reflects the severity of bronchial asthma / Thai J Physiol Sci 18 : 35 ~ 40
Bottcher MF / 2002 / Total and allergen-specific immunoglobulin A levels in saliva in relation to the development of allergy in infants up to 2 years of age / Clin Exp Aller
Fraser NG / 1969 / Immunoglobulins in dermatitis herpetiformis and various other skin diseases / Br J Dermatol 81 : 89 ~ 95
Gleeson M / 1996 / Development of bronchial hyperreactivity following transient absence of salivary IgA / Am J Respir Crit Care Med 153 (6 Pt 1) : 1785 ~ 1789
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