지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제2권 제5호
- 발행연도
- 2014.1
- 수록면
- 383 - 386 (4page)
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초록· 키워드
오류제보하기
Anaphylaxis to proton pump inhibitors (PPIs) has rarely been reported. Different patterns of cross-reactivity between PPIs have also been demonstrated using skin tests. Here, we report a case of anaphylaxis to lansoprazole with tolerance to other commercially available PPIs, which was proved by skin tests and oral provocation tests (OPTs). A 47-year-old female patient visited our Emergency Department with a sudden onset of whole body urticaria, facial swelling, dyspnea, and loss of consciousness that developed 1 hour after ingestion of 30 mg of lansoprazole for her episodic epigastric soreness. The skin prick test (SPT) and the intradermal test (IDT) with lansoprazole, esomeprazole, rabeprazole, and pantoprazole were performed. Lansoprazole showed positive reactions in both the SPT (3 mg/mL) and the IDT (0.003 mg/mL). Rabeprazole (3 mg/mL) showed a positive reaction only in IDT. The SPT and the IDT with esomeprazole and pantoprazole were all negative. The OPT with 30 mg of lansoprazole was positive (showing generalized rash and facial swelling 30 minuites after ingestion), while OPTs with esomeprazole, pantoprazole, and rabeprazole were all negative. Other PPIs could be safe alternatives in cases of anaphylaxis to 1 PPI. Skin tests seem to be helpful to define cross-reactivity between PPIs.
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참고문헌 (15)
참고문헌 신청
Bonadonna P / 2012 / Hypersensitivity to proton pump inhibitors: diagnostic accuracy of skin tests compared to oral provocation test / J Allergy Clin Immunol 130 : 547 ~ 549
Bose S / 2013 / Evaluation and management of hypersensitivity to proton pump inhibitors / Ann Allergy Asthma Immunol 111 : 452 ~ 457
Chang YS / 2012 / Hypersensitivity reactions to proton pump inhibitors / Curr Opin Allergy Clin Immunol 12 : 348 ~ 353
Choi SW / 2012 / Lessons from two cases of anaphylaxis to proton pump inhibitors / J Clin Pharm Ther 37 : 614 ~ 616
Demirkan K / 2006 / Anaphylactic reaction to drugs commonly used for gastrointestinal system diseases: 3 case reports and review of the literature / J Investig Allergol Clin
Bose S / 2013 / Evaluation and management of hypersensitivity to proton pump inhibitors / Ann Allergy Asthma Immunol 111 : 452 ~ 457
Chang YS / 2012 / Hypersensitivity reactions to proton pump inhibitors / Curr Opin Allergy Clin Immunol 12 : 348 ~ 353
Choi SW / 2012 / Lessons from two cases of anaphylaxis to proton pump inhibitors / J Clin Pharm Ther 37 : 614 ~ 616
Demirkan K / 2006 / Anaphylactic reaction to drugs commonly used for gastrointestinal system diseases: 3 case reports and review of the literature / J Investig Allergol Clin
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