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학술저널
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대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제1권 제4호
발행연도
2013.1
수록면
370 - 376 (7page)

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Purpose: To investigate the clinical characteristics and the risk factors for mechanical ventilator treatment and incidence of complications in children admitted to an intensive care unit (ICU) with detected respiratory viruses. Methods: Eighty-two patients who were detected respiratory viruses by multiplex real-time polymerase chain reaction from nasopharyngeal aspirates were enrolled among the 123 children admitted to ICU with acute respiratory manifestations during the study period from January 2006 to December 2012. Results: Detection rate of respiratory viruses were 66% and 13 patients (16%) had two viruses isolated. The most common respiratory virus isolated was respiratory syncytial virus (RSV) (35%) followed by rhinovirus (19%), adenovirus (13%), parainfluenza virus (11%), influenza virus (11%), human metapneumovirus (6%), and human coronavirus (5%). Pneumonia (70%) was the most common clinical diagnosis. The mean age of patient with RSV infection was the youngest and with influenza virus infection was the oldest among other viruses infection (mean±standard deviation, 5.9±10.1 months vs. 51.0±26.1 months; P=0.01). Forty Patients (49%) who had the underlying diseases were not associated with incidence of mechanical ventilator treatment and complications. Bacterial coinfection with respiratory virus was the significant risk factor of mechanical ventilator care and incidence of complications (odds ratio [OR], 50.003; 95% confidence interval [CI], 3.955–632.144; P=0.003, and OR, 15,569; 95% CI, 1.803–134.452; P=0.013). Conclusion: The significant morbidity of pediatric patient admitted to ICU with respiratory virus infection (RVI) was associated with bacterial coinfection. Furthermore, multicenter study should be performed to investigate the epidemiology of RVI in pediatric patients admitted to ICU in domestic.
#Respiratory virus #Intensive care units #Child

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참고문헌 (22)

참고문헌 신청
Aramburo A / 2011 / Role of real-time reverse transcription polymerase chain reaction for detection of respiratory viruses in critically ill children with respiratory disease google schola Crowcroft NS / 2008 / Respiratory syncytial virus infection in infants admitted to paediatric intensive care units in London, and in their families / Eur J Pediatr 167 : 395 google schola Diniz EM / 2005 / Incidence of respiratory viruses in preterm infants submitted to mechanical ventilation / Rev Inst Med Trop Sao Paulo 47 : 37 ~ 44 google schola Farias JA / 2012 / Mechanical ventilation in pediatric intensive care units during the season for acute lower respiratory infection: a multicenter study / Pediatr Crit Care google schola Ghani AS / 2012 / An investigation into the prevalence and outcome of patients admitted to a pediatric intensive care unit with viral respiratory tract infections in Cape Tow google schola

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