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학술저널
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대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제3권 제6호
발행연도
2015.1
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402 - 409 (8page)

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Purpose: The purpose of this study is to identify the epidemiologic and clinical characteristics of respiratory adenovirus infections in children, and to investigate the difference in the clinical features between single adenovirus infection and coinfection with adenovirus and other respiratory viruses. Methods: A retrospective study was performed in 470 children hospitalized with respiratory adenovirus infections in Gwangmyeong Sungae Hospital between January 2013 and December 2013. Results: The mean age of the patients was 46.2 months and the peak incidence was in the 12- to 24-month age group. The mean duration of hospitalization and fever were 4.5±1.1 and 4.5±9.2 days, respectively. Seasonally it had occurred throughout the year, but showed the highest prevalence in August and high prevalence in July, September, and October. The frequency of viral coinfection with other respiratory viruses was 39.6%. The age was significantly younger in coinfection group than in the single adenovirus infection group (P<0.001). The prevalence rates of bronchiolitis (P<0.001) and pneumonia (P=0.042) were significantly higher in the respiratory syncytial virus coinfection group. The coinfection rate was significantly higher in children aged less than 2 years (P<0.001), and the prevalence rates of bronchiolitis (P<0.001) and pneumonia (P<0.001) were also higher in the group aged less than 2 years than other age groups. Conclusion: Adenovirus is an important viral agent in hospitalized children with acute respiratory tract infection. Lower respiratory tract infections, such as bronchiolitis and pneumonia, and coinfection with other respiratory viruses were more frequently occurred in patients under 2 years of age. Further studies are needed to clarify whether coinfection with other respiratory viruses would increase the rate of lower respiratory tract infections in patients with respiratory adenoviral infections.
#Adenovirus #Respiratory adenoviral infection #Coinfection #Child #Hospitalization

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참고문헌 (25)

참고문헌 신청
Abzug MJ / 1991 / Neonatal adenovirus infection : four patients and review of google schola Alharbi S / 2012 / Epidemiology of severe pediatric adenovirus lower respiratory tract infections in Manitoba, Canada, 1991-2005 / BMC Infect Dis 12 : 55 ~ google schola Calvo C / 2008 / Multiple simultaneous viral infections in infants with acute respiratory tract infections in Spain / J Clin Virol 42 : 268 ~ 272 google schola Canducci F / 2008 / Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute re google schola Chang SY / 2008 / A community-derived outbreak of adenovirus type 3 in children in Taiwan between 2004 and 2005 / J Med Virol 80 : 102 ~ 112 google schola

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