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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제49권 제5호
- 발행연도
- 2015.1
- 수록면
- 413 - 417 (5page)
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We report a rare case of oncocytic renal cell carcinoma (RCC) with tubulopapillary growth in the background of tuberculous end-stage kidney disease. Histology of the renal mass consisted of oncocytic cells forming solid, thin tubules and rare papillae. The tumor had abundant eosinophilic oncocytic cells containing occasional cytoplasmic Mallory body–like hyaline globules and a tiny focus of clear cells with intervening mature fat. Both the oncocytic cells and clear cells were immunoreactive for a-methylacyl-CoA racemase, vimentin, pancytokeratin, and CD10, and negative for transcription factor E3, CD15, human melanoma black 45, and c-kit. Mallory body–like hyaline globules were positive for CAM 5.2 and periodic acid–Schiff with or without diastase. Ultrastructurally, the tumor cells had abundant cytoplasmic mitochondria. The present case is a rare case of oncocytic RCC with tubulopapillary growth pattern. The case is unique in that the tumor was mixed with fat component, which is not common in RCC and thus can lead to misdiagnosis.
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참고문헌 (10)
참고문헌 신청
Aron M / 2010 / Renal cell carcinomas with intratumoral fat and concomitant angiomyolipoma : potential pitfalls in staging and diagnosis / Am J Clin Pathol 134 : 807 ~ 812
Datta BN / 1977 / Hyaline intracytoplasmic globules in renal carcinoma / Arch Pathol Lab Med 101 : 391 ~
Eble JN / 2004 / World Health Organization classification of tumours: pathology and genetics of tumours of the urinary system and male genital organs / IARC Press
Kunju LP / 2008 / Papillary renal cell carcinoma with oncocytic cells and nonoverlapping low grade nuclei: expanding the morphologic spectrum with emphasis on clinicopatholog
Mai KT / 2008 / Oncocytic papillary renal cell carcinoma with solid architecture : mimic of renal oncocytoma / Pathol Int 58 : 164 ~ 168
Datta BN / 1977 / Hyaline intracytoplasmic globules in renal carcinoma / Arch Pathol Lab Med 101 : 391 ~
Eble JN / 2004 / World Health Organization classification of tumours: pathology and genetics of tumours of the urinary system and male genital organs / IARC Press
Kunju LP / 2008 / Papillary renal cell carcinoma with oncocytic cells and nonoverlapping low grade nuclei: expanding the morphologic spectrum with emphasis on clinicopatholog
Mai KT / 2008 / Oncocytic papillary renal cell carcinoma with solid architecture : mimic of renal oncocytoma / Pathol Int 58 : 164 ~ 168
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