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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제49권 제6호
- 발행연도
- 2015.1
- 수록면
- 427 - 437 (11page)
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초록· 키워드
오류제보하기
Central nervous system (CNS) neoplasms are the second most common childhood malignancy after leukemia and the most common solid organ neoplasm in children. Diagnostic dilemmas with small specimens from CNS neoplasms are often the result of multifactorial etiologies such as frozen or fixation artifact, biopsy size, or lack of knowledge about rare or unfamiliar entities. Since the late 1950s, ultrastructural examination has been used in the diagnosis of CNS neoplasms, though it has largely been replaced by immunohistochemical and molecular cytogenetic studies. Nowadays, pathologic diagnosis of CNS neoplasms is achieved through intraoperative cytology, light microscopy, immunohistochemistry, and molecular cytogenetic results. However, the utility of electron microscopy (EM) in the final diagnosis of CNS neoplasms and investigation of its pathogenetic origin remains critical. Here, we reviewed the distinguishing ultrastructural features of pediatric CNS neoplasms and emphasize the continuing value of EM in the diagnosis of CNS neoplasms.
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참고문헌 (25)
참고문헌 신청
Ahsan J / 2015 / Spectrum of central nervous system tumours : a single center histopathological review of 761 cases over 5 years / J Ayub Med Coll Abbottabad 27 : 81 ~ 84
Buccoliero AM / 2011 / Pediatric rhabdoid meningioma: a morphological, immunohistochemical, ultrastructural and molecular case study / Neuropathology 31 : 59 ~ 65
Couce ME / 2000 / Chordoid meningioma: a clinicopathologic study of 42 cases / Am J Surg Pathol 24 : 899 ~ 905
Donato G / 2006 / Chordoid meningioma : case report and literature review / Ultrastruct Pathol 30 : 309 ~ 314
Gerstner ER / 2010 / Primary central nervous system lymphoma / Arch Neurol 67 : 291 ~ 297
Buccoliero AM / 2011 / Pediatric rhabdoid meningioma: a morphological, immunohistochemical, ultrastructural and molecular case study / Neuropathology 31 : 59 ~ 65
Couce ME / 2000 / Chordoid meningioma: a clinicopathologic study of 42 cases / Am J Surg Pathol 24 : 899 ~ 905
Donato G / 2006 / Chordoid meningioma : case report and literature review / Ultrastruct Pathol 30 : 309 ~ 314
Gerstner ER / 2010 / Primary central nervous system lymphoma / Arch Neurol 67 : 291 ~ 297
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