지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제45권 제3호
- 발행연도
- 2011.1
- 수록면
- 296 - 302 (7page)
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초록· 키워드
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Background: The preparation of conventional smears (CS) from mucoid samples, despite mucolysis, can pose difficulties for cytotechnologists or cytopathologists. In recent years, liquid-based cytology (LBC) devices have been developed in attempts to improve the cytopreparation process. LBC improves both sample collection and sample preparation. Cell block preparations (CB) can be made from residual tissue fluids, and are a useful adjunct to smears. Methods: We retrospectively reviewed 3 preparations from 209 patients whose diagnosis was later confirmed via bronchoscopic biopsy, fine needle aspiration, gun biopsy or operation. Each case was categorized into one of three groups: “negative,” “atypical or suspicious” and “malignant.” Results: When conflating the “atypical” and “malignant” categories into a “positive” category, the sensitivity of each preparation was 74.4% in LBC, 72.9% in CS, and 76.5% in CB preparations. Specificity was 98.7%, 94.7% and 98.7%, respectively. By combining LBC and CB, the sensitivity is 78.2%. Conclusions: Among three different preparation methods, sensitivity is highest in the CB method. LBC has many advantages in evaluating cell morphology and by combining CB method, the sensitivity can be improved slightly. The application of all three methods may prove helpful when one or another method proves diagnostically inconclusive.
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참고문헌 (20)
참고문헌 신청
Calabretto ML / 1996 / Diagnostic utility of cell-block from bronchial washing in pulmonary neoplasms / Diagn Cytopathol 15 : 191 ~ 192
Chaudhary BA / 1978 / Fiberoptic bronchoscopy: comparison of procedures used in the diagnosis of lung cancer / J Thorac Cardiovasc Surg 76 : 33 ~ 37
Choi YD / 2008 / Effectiveness of sputum cytology using ThinPrep (R) method for evaluation of lung cancer / DIAGNOSTIC CYTOPATHOLOGY 36 (3) : 167 ~ 171
Elsheikh TM / 2006 / Comparison of ThinPrep and cytospin preparations in the evaluation of exfoliative cytology specimens / Cancer 108 : 144 ~ 149
Grunze H / 1973 / Cytologic diagnosis of tumors of the chest / Acta Cytol 17 : 148 ~ 159
Chaudhary BA / 1978 / Fiberoptic bronchoscopy: comparison of procedures used in the diagnosis of lung cancer / J Thorac Cardiovasc Surg 76 : 33 ~ 37
Choi YD / 2008 / Effectiveness of sputum cytology using ThinPrep (R) method for evaluation of lung cancer / DIAGNOSTIC CYTOPATHOLOGY 36 (3) : 167 ~ 171
Elsheikh TM / 2006 / Comparison of ThinPrep and cytospin preparations in the evaluation of exfoliative cytology specimens / Cancer 108 : 144 ~ 149
Grunze H / 1973 / Cytologic diagnosis of tumors of the chest / Acta Cytol 17 : 148 ~ 159
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