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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제36권 제1호
- 발행연도
- 2002.1
- 수록면
- 55 - 58 (4page)
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A case of primary gastric choriocarcinoma with multiple liver metastases is described. A 54-
year-old man underwent gastrectomy for an advanced cancer. An ulcerofungating tumor with extensive hemorrhagic necrosis was found in the anterior wall of the prepyloric antrum. The histologic examination revealed a biphasic pattern composed of uninucleated cyto or intermediate trophoblasts and syncytiotrophoblasts. A small area of the adenocarcinoma forming
glandular structures and poorly differentiated solid sheets was also noted on the superficial
portion of the tumor. Immunohistochemical staining for the beta human chorionic gonadotropin (β-hCG) and the human placental lactogen (hPL) showed strong immunoreactivity, particularly in the cytoplasms of the syncytiotrophoblasts and intermediate trophoblasts, respectively. A diagnosis of the choriocarcinoma was made. Multiple hepatic nodules consistent with
metastases were noted on the abdominal sonogram. The serum β-hCG level of the patient was significantly increased.
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