지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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We developed a web-based Y chromosomal short tandem repeat (Y-STR) database (ySTRmanager, http://ystrmanager.yonsei.ac.kr) to facilitate calculation of YSTR haplotype frequency estimates for random matches and kinship indices for various relationship levels. The ySTRmanager database provides 3 functions: (i) Y-STR haplotype search, (ii) kinship index calculation, and (iii) user database configuration.
The Y-STR haplotype search function allows researchers to retrieve Y-STR haplotypes that meet queried Y-STR allele, Y-haplogroup affiliation, and/or sample information from a selected population in the open database, which consists of 12-17 Y-STR loci. The number of matches in a selected population, haplotype frequency estimator,and detailed results for matched and neighbor haplotypes are displayed as a set of search results. The kinship index calculation function provides kinship indices of 2input Y-STR haplotypes for the relationship represented by the number of meioses,with consideration of target population and mutation rate of each Y-STR. In addition,ySTRmanager allows registered users to configure their own database to store and analyze Y-STR haplotype and/or mutation rate data. The stored Y-STR data can be used in the search function and in the analysis to obtain forensic statistical values. The ySTRmanager will be a useful system to analyze and manage Y-STR data in the practice of forensic genetics.
목차
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참고문헌 (27)
참고문헌 신청
/ / Summary list of Y chromosome STR loci and available fact sheets
Buckleton JS / 2005 / Forensic DNA evidence interpretation. 1st ed / CRC press : 388 ~ 389
Buckleton JS / 2011 / The interpretation of lineage markers in forensic DNA testing / Forensic Sci Int Genet 5 : 78 ~ 83
Clopper CJ / 1934 / The use of confidence or fiducial limits illustrated in the case of the binomial / Biometrika 26 : 404 ~ 413
Decker AE / 2008 / Analysis of mutations in father-son pairs with 17 Y-STR loci / Forensic Sci Int Genet 2 : 31 ~ 35
Buckleton JS / 2005 / Forensic DNA evidence interpretation. 1st ed / CRC press : 388 ~ 389
Buckleton JS / 2011 / The interpretation of lineage markers in forensic DNA testing / Forensic Sci Int Genet 5 : 78 ~ 83
Clopper CJ / 1934 / The use of confidence or fiducial limits illustrated in the case of the binomial / Biometrika 26 : 404 ~ 413
Decker AE / 2008 / Analysis of mutations in father-son pairs with 17 Y-STR loci / Forensic Sci Int Genet 2 : 31 ~ 35
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