지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Ethambutol is commonly used as a first-line drug for the treatment of tuberculosis. The most serious adverse effect of ethambutoltherapy is optic neuropathy. However, ethambutol-induced acute kidney injury is extremely rare. We report herein a case of acutekidney injury secondary to ethambutol-associated acute interstitial nephritis. A 65-year-old man with pulmonary tuberculosispresented with a > 7-day history of nausea and vomiting. He had begun antituberculosis medications including ethambutol 3 weekspreviously. His laboratory findings showed elevated blood urea nitrogen and serum creatinine levels (32.6 and 3.6 mg/dL,respectively). Examination of percutaneous renal biopsy specimens showed diffuse interstitial mononuclear cell infiltration withmild interstitial edema. The patient was treated by cessation of ethambutol and supportive care. His renal function completely recovered(creatinine, 1.1 mg/dL) and his clinical symptoms improved.
목차
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참고문헌 (10)
참고문헌 신청
Chan RY / 2006 / Ocular toxicity of ethambutol / Hong Kong Med J 12 : 56 ~ 60
Cole A / 1981 / Metal binding by pharmaceuticals: part 1. copper (II) and zinc (II) interactions following ethambutol administration / Agents Actions 11 : 296 ~ 305
Forbes M / 1966 / Effect of ethambutol on Mycobacteria / Ann N Y Acad Sci 135 : 726 ~ 731
Hasenbosch RE / 2008 / Ethambutol-induced optical neuropathy: risk of overdosing in obese subjects / Int J Tuberc Lung Dis 12 : 967 ~ 971
Joint Committee for the Development of Korean Guidelines for Tuberculosis / 2011 / Korean Guidelines for Tuberculosis / MEDrang Inc
Cole A / 1981 / Metal binding by pharmaceuticals: part 1. copper (II) and zinc (II) interactions following ethambutol administration / Agents Actions 11 : 296 ~ 305
Forbes M / 1966 / Effect of ethambutol on Mycobacteria / Ann N Y Acad Sci 135 : 726 ~ 731
Hasenbosch RE / 2008 / Ethambutol-induced optical neuropathy: risk of overdosing in obese subjects / Int J Tuberc Lung Dis 12 : 967 ~ 971
Joint Committee for the Development of Korean Guidelines for Tuberculosis / 2011 / Korean Guidelines for Tuberculosis / MEDrang Inc
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